Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26465 |
A1-226
A1226 |
Others | Others |
A1-226 is a cephalosporin of the class of β-lactam antibiotics, it is originally derived from the fungus Acremonium. | |||
T36084 |
PKI-179
|
Others | Others |
PKI-179 is a potent and orally active dual PI3K/mTOR inhibitor, with IC50s of 8 nM, 24 nM, 74 nM, 77 nM, and 0.42 nM for PI3K-α, PI3K-β, PI3K-γ, PI3K-δ and mTOR, respectively. PKI-179 also exhibits activity over E545K and H1047R, with IC50s of 14 nM and 11 nM, respectively. PKI-179 shows anti-tumor activity in vivo[1][2]. PKI-179 inhibits the cell proliferation, with IC50s of 22 nM and 29 nM for MDA361 and PC3 cells, respectively[1].PKI-179 shows inhibitory activity against a panel of 361 other ... |