Cat. No. | Product Name | Target | Signaling Pathways |
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T38323 |
A-943931 (hydrochloride hydrate)
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A-943931 is a histamine H4receptor antagonist (Ki= 3.8 nM).1In vivo, A-943931 inhibits scratching induced by clobenpropit in mice (ED50= 26 μmoles/kg, i.p.). 1.Milicic, I., Witte, D.G., Miller, T.L., et al.Identification of two potent and selective histamine H4 receptor antagonists with antipruritic activityFASEB J.23(S1)760.768-760.768(2009) | |||
T73352 |
A-943931
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A-943931 是一种有效的选择性组胺 H4 受体拮抗剂,对人和大鼠 H4R 的 Ki 值分别为 4.6、3.8 nM。A-943931 具有抗炎和抗伤害作用。 |