Cat. No. | Product Name | Target | Signaling Pathways |
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T36165 |
8-iso-13,14-dihydro-15-keto Prostaglandin F2α
8-iso-13,14-dihydro-15-keto Prostaglandin F2α |
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8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits, monkeys and humans. 8-iso PGF2α is a PG-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-isoprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-isoprostane is infused into ra... |