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Cat. No. | Product Name | Target | Signaling Pathways |
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T40455 |
8-NH2-ATP
8-Aminoadenosine-5'-O-triphosphate,8-NH2-ATP |
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8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado. It has been documented that 8-NH2-Ado exhibits potent properties, as evidenced by its ability to induce apoptosis-associated cleavage of poly(ADP-ribose) polymerase. |
Cat. No. | Product Name | Target | Signaling Pathways |
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T40483 |
8-Aminoadenosine
8-NH2-Ado,8-氨基腺苷 |
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8-Aminoadenosine (8-NH2-Ado) is an RNA-directed nucleoside analogue that effectively diminishes cellular ATP levels and impedes mRNA synthesis. Furthermore, it effectively obstructs Akt/mTOR signaling, inducing autophagy and apoptosis in a p53-independent manner. Its significant antitumor activity further highlights its therapeutic potential. |