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Cat. No. Product Name Target Signaling Pathways
T38128 Leukotriene D4

Leukotriene D4 MaxSpec® Standard,LTD4

Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. It is the first cysteinyl-leukotriene metabolite of LTC4 . Like LTC4, LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. LTD4 is equipotent to LTC4 in its biological activities, except that LTD4 is nearly 100-fold more effective in the contraction of...
T37493 11-trans Leukotriene D4

11-trans Leukotriene D4

11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.

化合物

Leukotriene D4
Cat.No: T38128
Synonym: Leukotriene D4 MaxSpec® Standard,LTD4
Target:
11-trans Leukotriene D4
Cat.No: T37493
Synonym: 11-trans Leukotriene D4
Target:
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