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Cat. No. | Product Name | Target | Signaling Pathways |
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T70856 |
3-Oxobetulin Acetate
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3-Oxobetulin acetate is a derivative of the cholesterol biosynthesis inhibitor betulin. It inhibits the growth of P388 murine lymphocytic leukemia cells (EC50 = 0.12 µg/ml), as well as human MCF-7 breast, SF-268 CNS, H460 lung, and KM20L2 colon cancer cells (GI50s = 8, 10.6, 5.2, and 12.7 µg/ml, respectively), but not BxPC-3 pancreas or DU145 prostate cancer cells (GI50s = >10 µg/ml for both). 3-Oxobetulin acetate inhibits replication of X4 tropic recombinant HIV (NL4.3-Ren) in MT-2 lymphoblasto... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN2446 |
3-Oxobetulin
Betulone |
Antiviral | Immunology/Inflammation |
Betulone is a triterpenoid. It has a role as a metabolite. It derives from a hydride of a lupane. |