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Cat. No. Product Name Target Signaling Pathways
T23239 Ro 04-5595 hydrochloride

Others Others
NR2B-containing NMDA receptors antagonist
T70049 Ro 04-5595 free base

Ro 04-5595 is a selective antagonist of NMDA receptors NR2B subunits. Ro 04-5595 had an EC 50 of 186 ± 32 nmol/L. Ro 04-5595 was predicted to bind the EVT-101 binding site, not the ifenprodil-binding site. Specific binding, defined with a new NR2B-specific antagonist Ro 04-5595 at 10 microM was fully inhibited by several compounds with the following rank order of affinities--Ro 25-6981 > CP-101,606 > Ro 04-5595 = ifenprodil >> eliprodil > haloperidol > spermine > spermidine > MgCl2 > CaCl2--and...

化合物

Ro 04-5595 hydrochloride
Cat.No: T23239
Synonym:
Target: Others
Ro 04-5595 free base
Cat.No: T70049
Synonym:
Target:
TargetMol Loading
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