Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4105 |
AFN-1252
Debio 1452,API-1252 |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
AFN-1252 (Debio 1452)是一种FabI 的高效抑制剂,能抑制金黄色葡萄球菌。 | |||
T4105L |
AFN-1252 tosylate
API-1252 tosylate |
||
AFN-1252 tosylate is an enoyl-ACP Reductase inhibitor. | |||
T71539 | AFN-1252 tosylate hydrate | ||
AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is FASII Inhibitor which is potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 efficiently blocked daptomycin-induced phospholipid decoy production, even in the case of isolates resistant to AFN-1252, which prevented the inactivation of daptomyci... |