Cat. No. | Product Name | Target | Signaling Pathways |
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T21029 |
Norfluoxetine Hydrochloride
Norfluoxetine HCl,去甲氟西汀 |
Others | Others |
Norfluoxetine Hydrochloride (Norfluoxetine HCl) 是氟西汀的活性代谢物。氟西汀是一种抗抑郁药。 | |||
T71302 |
Norfluoxetine-d5 HCl
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Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa... | |||
T26184 |
Seproxetine HCl
(S)-Norfluoxetine hydrochloride,Seproxetine hydrochloride,(S)-Desmethylfluoxetine Hydrochloride |
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Seproxetine HCl, a more active enantiomer of N-desmethyl metabolite fluoxetine, works by selectively inhibiting the serotonin uptake carrier. |