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Cat. No. Product Name Target Signaling Pathways
T37303 5-OxoETE

5-KETE,5-OxoETE

5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.[1] It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM.[2] 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils via a specific G protein-coupled receptor.[3],[4],[5],[6]
T37304 5-OxoETE methyl ester

5-OxoETE methyl ester is an esterified form of the polyunsaturated keto acid 5-oxoETE . 5-OxoETE methyl ester is an agonist of oxoeicosanoid receptor 1 (OXER1; EC50 = 1.54 μM for β-arrestin recruitment) that has a higher maximal response than 5-oxoETE in a β-arrestin assay.

化合物

5-OxoETE
Cat.No: T37303
Synonym: 5-KETE,5-OxoETE
Target:
5-OxoETE methyl ester
Cat.No: T37304
Synonym:
Target:
TargetMol Loading
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