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Search Results for " 3α-hsd "

4

抑制剂 & 化合物

1

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T79886	HSD17B13-IN-3
	HSD17B13-IN-3（化合物2）是一种有效的HSD17B13抑制剂，但不具备细胞实验活性。
T62236	Steroid sulfatase/17β-HSD1-IN-3
	Steroid sulfatase/17β-HSD1-IN-3 (compound 19) 是一种双重的类固醇硫酸酯酶 (STS) 和 17β-羟基类固醇脱氢酶 1 型 (17β HSD1) 抑制剂。Steroid sulfatase/17β-HSD1-IN-3 对 hSTS 的活性具有不可逆的抑制作用 (IC50: 27 nM)。Steroid sulfatase/17β-HSD1-IN-3 能够用于研究子宫内膜异位症及其他雌激素依赖性疾病。
T0992	Carbenoxolone disodium Biogastrone,Duogastrone,甘珀酸钠,Bioral	Gap Junction Protein	Cytoskeletal Signaling
	Carbenoxolone disodium (Duogastrone) 是甘草酸的活性代谢物和人11β-HSD 和细菌3α, 20β-HSD 的抑制剂。它是一种缝隙连接的解耦剂，可抑制牛痘病毒生长，用于消化性、食道和口腔溃疡和炎症的相关研究。
T76147	3α-Hydroxysteroid dehydrogenase
	3α-Hydroxysteroid dehydrogenase(3α-HSD) 是一种由 AKR1C4 基因编码的酶，可以催化 3-酮类甾体转化为 3α-羟基化合物。3α-Hydroxysteroid dehydrogenase 在雄激素 DHT 的失活中起重要作用，可以将 DHT 转化成雄激素活性很弱的 3α-雄烷二醇，可用于多毛症研究。

化合物

HSD17B13-IN-3

Cat.No: T79886

Steroid sulfatase/17β-HSD1-IN-3

Cat.No: T62236

Carbenoxolone disodium

Cat.No: T0992

Synonym: Biogastrone,Duogastrone,甘珀酸钠,Bioral

Target: Gap Junction Protein

3α-Hydroxysteroid dehydrogenase

Cat.No: T76147

Cat. No.	Product Name	Target	Signaling Pathways
T12353	Palbinone	Others	Others
	Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, with anti-inflammatory activity.

天然产物

Cat.No: T12353

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03859	DHRS9 Protein, Human, Recombinant (His) 3α-HSD,RDHTBE,3ALPHA-HSD,RDH-E2,R...	Human	E. coli
	Dehydrogenase/reductase (SDR family) member 9 (DHRS9) is aberrantly expressed in colorectal cancer (CRC), the decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic biomarker in CRC. The human regulatory macrophage (Mreg) has emerged as a promising cell type for use as a cell-based adjunct immunosuppressive therapy in solid organ transplant recipients. DHRS9 is a specific and stable marker of human Mregs.
TMPH-00851	HSD3B1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	HSD3B1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.4 kDa and the accession number is P14060.
TMPH-03654	Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)	VACV	E. coli
	Catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. During viral infection, steroid production contributes to virulence by inhibiting the host inflammatory response. Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted...

重组蛋白

DHRS9 Protein, Human, Recombinant (His)

Cat.No: TMPY-03859

Species: Human

Expression System: E. coli

HSD3B1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00851

Species: Human

Expression System: E. coli

Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)

Cat.No: TMPH-03654

Species: VACV

Expression System: E. coli

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