Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T69418 |
AM-679
|
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AM-679 is a 5-lipoxygenase-activating protein (FLAP) inhibitor. | |||
T14205 |
AM679
|
Others | Others |
AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively. IC50 value: 2.2 nM/0.6 nM/154 nM(FLAP binding/hLA/hWB) [1] AM679 showed an improved CYP inhibition profile (IC50 3A4 = 16.7 lM, 2C9 = |