Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26789 |
BH3I-2'
BH3I2',BH3I 2' |
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BH3I-2' is a cell-permeable BH3 mimetic. BH3I-2' induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the interaction between Bcl-x and Bak BH3 by targeting the Bcl-x binding pocket. |