Cat. No. | Product Name | Target | Signaling Pathways |
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T38206 |
3-Cysteinylacetaminophen (trifluoroacetate salt)
APAP-Cys,3-(cysteine-S-yl)acetaminophen,3-Cysteinylacetaminophen (trifluoroacetate salt) |
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3-Cysteinylacetaminophen is an acetaminophen-protein adduct formed during the metabolism of acetaminophen.[1],[2] 3-Cysteinylacetaminophen has been found in isolated human serum following therapeutic and supratherapeutic doses of acetaminophen and in the presence and absence of hepatotoxicity.[3],[4] In mice, 3-cysteinylacetaminophen decreases renal glutathione (GSH) levels, an effect that can be blocked by the γ-glutamyl inhibitor acivicin. |