Cat. No. | Product Name | Target | Signaling Pathways |
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T61362 |
CDK5-IN-3
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CDK5-IN-3 (compound 11) is a highly potent and selective inhibitor of CDK5, demonstrating significant inhibition with IC50 values of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. This compound holds promise for further investigation in the context of autosomal dominant polycystic kidney disease (ADPKD) research [1]. |