Cat. No. | Product Name | Target | Signaling Pathways |
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T40255 |
VCP/p97 inhibitor-1
VCP/p97 inhibitor-1 |
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VCP/p97 inhibitor-1, a highly effective compound, inhibits VCP/p97 (also known as Cdc48, CDC-48, or Ter94) with an IC 50 of 54.7 nM. This inhibitor induces a disruption in protein homeostasis and interferes with the degradation process of misfolded polypeptides by the ubiquitin-proteasome system (UPS). |