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Cat. No. Product Name Target Signaling Pathways
T61501 Topoisomerase I inhibitor 5

Topoisomerase I inhibitor 5 is an efficient inhibitor of topoisomerase I, with an IC50 value. It effectively disrupts DNA and inhibits the activity of topoisomerase I. Moreover, it can induce apoptosis in MCF-7 cells and arrest the cell cycle at the G1 phase. Topoisomerase I inhibitor 5 also exhibits potency in reversing P-gp-mediated resistance to Adriamycin [1].

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Topoisomerase I inhibitor 5
Cat.No: T61501
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