Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11559 |
HG-12-6
|
Others | Others |
HG-12-6 is a type II inhibitor of IRAK4. HG-12-6 shows preferential binding to unphosphorylated inactive IRAK4 (IC50: 165 nM). HG-12-6 can modulate IRAK4 activity in autoimmunity and inflammation. |