Cat. No. | Product Name | Target | Signaling Pathways |
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T39672 |
Ac-Ile-Glu-Thr-Asp-pNA
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Ac-Ile-Glu-Thr-Asp-pNA is a caspase-8 substrate that undergoes enzymatic binding and cleavage specifically at the Ile-Glu-Thr-Asp (IETD) peptide sequence. This cleavage results in the release of p-nitroalinide, which can be quantitatively measured using colorimetric detection at 405 nm. This measure serves as an indicator of caspase-8 enzyme activity. |