Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11314 |
Fosmanogepix
APX001,E1211 |
Others | Others |
Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This metabolism leads to the formation of the active moiety, APX001A. Fosmanogepix (APX001), with its ability to target the highly conserved Gwt1 fungal enzyme, holds great potential for the development of treatments against invasive fungal infections. | |||
T23749 |
APX001
APX 001,APX-001 |
||
APX001 is a prodrug of APX-001A. APX001 is the first-in-class inhibitor of the fungal protein Gwt1. |