Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11118 |
Duocarmycin SA
|
Others | Others |
Duocarmycin SA is an extremely potent cytotoxic agent and antitumor antibiotic that induces sequence-selective alkylation of duplex DNA, with an IC50 of 10 pM. It demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells when combined with proton radiation in vitro. |