Cat. No. | Product Name | Target | Signaling Pathways |
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T36775 |
13,14-dihydro Prostaglandin E1
13,14-dihydro Prostaglandin E1 |
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13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hyb... | |||
T36147 |
13,14-dihydro-15-keto Prostaglandin E1
13,14-dihydro-15-keto Prostaglandin E1 |
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13,14-dihydro-15-keto Prostaglandin E1 可抑制 ADP 诱导的人离体富血小板血浆中的血小板聚集(IC50=14.8 μg/mL),也是 PGE1 代谢物。 |