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Cat. No. | Product Name | Target | Signaling Pathways |
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TP1232 |
Amylin, amide, rat
Amylin (rat) |
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Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a concentration-dependent decrease in ac | |||
TP1233 |
Amylin (8-37), rat
Amylin (8-37) (mouse, rat) |
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Amylin (8-37), rat is a truncated analog of native Amylin that selectively inhibits insulin-related glucose uptake and glycogen deposition in muscle tissue. Amylin is also known as islet amyloid precursor peptide (IAPP) and is co-secreted with insulin fro | |||
T35627 |
Amylin (human) (trifluoroacetate salt)
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Amylin is a 37-residue peptide hormone secreted from pancreatic β-cells that reduces food intake, decreases glucagon secretion, slows gastric emptying, and increases satiety. It binds to amylin receptors with IC50 values of 2 and 0.2 nM for porcine and guinea pig nucleus accumbens membrane preparations, respectively. Amylin is present in amyloid aggregates derived from the pancreatic islets of humans with type 2 diabetes. Amylin forms fibrils that react to thioflavin T and are organized in a cro... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TP1232L |
Amylin, amide, rat acetate(124447-81-0,free base)
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Amylin Receptor | GPCR/G Protein |
Amylin, amide, rat acetate(124447-81-0,free base) 是 AMY1 和 AMY3 受体以及 AMY2 受体的强效和高亲和力配体。 |