Cat. No. | Product Name | Target | Signaling Pathways |
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T36455 |
11β-Prostaglandin F2α
11β-Prostaglandin F2α |
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11β-Prostaglandin F2α 是一种由 AKR1C3 催化的生物活性代谢物,可刺激前列腺素 F 受体并诱导乳腺癌中的 slug 表达。11β-Prostaglandin F2α 也是存在于尿液中的内源代谢物。 | |||
T37275 |
2,3-dinor-11β-Prostaglandin F2α
2,3-dinor-11β-Prostaglandin F2α |
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2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2,3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2,3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α wh... |