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Cat. No. | Product Name | Target | Signaling Pathways |
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T38394L |
PSMα3 acetate(1001405-52-2 Free base)
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PSMα3 acetate(1001405-52-2 Free base) 是一种肽化合物,可用于诱导树突状细胞 (DC) 对 DC 疫苗接种策略的耐受性。PSMα3 acetate 通过改变 TLR2 或 TLR4 诱导的成熟过程,有效渗透和调节人类单核细胞衍生的 DC。 此外,PSMα3 acetate 可抑制促炎细胞因子和抗炎细胞因子的产生,并减少抗原摄取。 PSMα3 acetate 是大多数致病性耐甲氧西林金黄色葡萄球菌 (MRSA) 菌株释放的重要毒力因子。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T38394 |
PSMα3
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PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies. It effectively penetrates and modulates human monocyte-derived DCs by modifying the maturation process induced by TLR2 or TLR4. Additionally, PSMα3 inhibits the production of both pro- and anti-inflammatory cytokines and decreases antigen uptake. Notably, PSMα3 is a significant virulence factor released by the most pathogenic strains of methicillin-resistant Staphylococcus... |