首页工具

搜索结果

Search Results for " β-amyloid 1-16 "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
TP1228	β-Amyloid (1-16) Amyloid β-Protein (1-16),β-Amyloid 1-16
	β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is responsible for the formation of amyloid plaques in the brains of individuals affected by Alzheimer's disease (AD).
T80701	β Amyloid (1-16) rat
	β-Amyloid (1-16) rat 是β-淀粉样肽 (Abeta) 金属结合域的片段，含有三个与人类相异的氨基酸替代，因此在大鼠和小鼠中降低了 AD 样神经退行性变的易感性。
T76666	β-Amyloid peptide(16-20)
	β-Amyloid peptide(16-20)，即 Amyloid-β(Abeta) 的氨基酸序列(KLVFF)部分，有效抑制 Abeta 原纤维形成，通过在 N 和 C 末端添加 RG-/-GR-NH2 残基增强其溶解性。
T61397	AChE/BChE-IN-9
	AChE/BChE-IN-9 (Compound 7a) is a potent orally active inhibitor of AChE and BChE, with IC50 values of 5.74 μM and 14.05 μM against hAChE and eqBChE, respectively. It also demonstrates effective antioxidant activity, with an IC50 value of 57.35 μM. Additionally, AChE/BChE-IN-9 exhibits the ability to chelate iron and modulate the aggregation of amyloid β 1-42. Notably, AChE-IN-16 has the ability to cross the blood-brain barrier [1].
T36639	Donecopride (fumarate hydrate)
	Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= 3,530 nM) but does bind to 5-HT2Band sigma-2 (σ2) receptors (Ki= 1.6 nM for both) in a panel of 42 neurotransmitter receptors and transporters. Donecopride induces release of soluble amyloid precursor protein-α (sAPP-α) in COS-7 cells transiently expressing 5-HT4with an EC50value...