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Cat. No. Product Name Target Signaling Pathways
T6038 (-)-Blebbistatin

(S)-(-)-Blebbistatin

ATPase; Myosin Cytoskeletal Signaling; Membrane transporter/Ion channel
(-)-Blebbistatin ((S)-(-)-Blebbistatin) 是 blebbistatin 的 S 对映异构体。它是一种有效的选择性肌球蛋白 II 抑制剂,IC50 范围为 0.5 至 5 μM。
T36335 (S)-nitro-Blebbistatin

(S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin , which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (-)-Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM). Through these effects, it blocks apoptosis-related bleb formation, directed cell migration, and cytokinesis in vertebrate cells. H...
T71207 (R)-(+)-Blebbistatin O-Benzoate

(R)-(+)-Blebbistatin O-Benzoate is a derivative of Blebbistatin. (R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II. It blocks cell blebbing rapidly and reversibly and also disrupts directed cell migration and cytokinesis in vertebrate cell. (R)-(+)-Blebbistatin can also inhibit contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (R)-(+)-Blebbistatin is suitable as a negative control for (S)-(-)-...
T36400 para-amino-Blebbistatin

para-amino-Blebbistatin is a more water-soluble form of (S)-4'-nitro-blebbistatin , which is a more stable and less phototoxic form of (-)-blebbistatin .1,2,3 (-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases that rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM).2,3,4 Through these effects, it blocks ap...

化合物

(-)-Blebbistatin
Cat.No: T6038
Synonym: (S)-(-)-Blebbistatin
Target: ATPase, Myosin
(S)-nitro-Blebbistatin
Cat.No: T36335
Synonym:
Target:
(R)-(+)-Blebbistatin O-Benzoate
Cat.No: T71207
Synonym:
Target:
para-amino-Blebbistatin
Cat.No: T36400
Synonym:
Target:
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