keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Gap 26 是模拟肽,对应于连接蛋白 43 的残基 63-75,是间隙连接阻断剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 747 | 现货 | ||
2 mg | ¥ 987 | 现货 | ||
5 mg | ¥ 1,490 | 现货 | ||
10 mg | ¥ 2,320 | 现货 | ||
25 mg | ¥ 3,880 | 现货 | ||
50 mg | ¥ 5,530 | 现货 | ||
100 mg | ¥ 7,520 | 现货 |
产品描述 | Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker. |
体外活性 | Oscillatory behaviour was abolished by Gap 26 at concentrations of 100-300 microM (IC50 of 20-30 microM), without a change in average tone. No synergy was evident between peptides corresponding to the extracellular loops, and cytoplasmic loop peptides were biologically inactive [1]. Photoliberating InsP(3) in a single cell within a confluent culture triggered an intercellular calcium wave, which was inhibited by the connexin mimetic peptide gap 26 [2]. |
分子量 | 1550.78 |
分子式 | C70H107N19O19S |
CAS No. | 197250-15-0 |
keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 0.6448 mL | 3.2242 mL | 6.4484 mL | 16.1209 mL |
5 mM | 0.129 mL | 0.6448 mL | 1.2897 mL | 3.2242 mL | |
10 mM | 0.0645 mL | 0.3224 mL | 0.6448 mL | 1.6121 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Gap 26 197250-15-0 Cytoskeletal Signaling Gap Junction Protein Inhibitor Gap26 Gap-26 inhibit inhibitor