Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ascamycin 是一种由链霉菌属产生的 5'-O-磺酰胺核糖核苷抗生素,对黄单胞菌类显示出选择性的抗菌活性,对柠檬黄单胞菌、口蹄疫黄单胞菌和噬菌体具有抑制作用,MIC 值分别为0.4μg/mL、12.5μg/mL 和12.5μg/mL。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 2,350 | 现货 | ||
5 mg | ¥ 5,630 | 现货 | ||
10 mg | ¥ 7,790 | 现货 | ||
25 mg | ¥ 11,200 | 现货 | ||
50 mg | ¥ 13,800 | 现货 | ||
100 mg | ¥ 17,500 | 现货 | ||
500 mg | ¥ 34,800 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 5,370 | 现货 |
产品描述 | Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and inhibits Xanthomonas citri, Xanthomonas oryzae and phage with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL respectively. |
靶点活性 | Mycobacterium phlei:12.5 μg/ml, Xanthomonas oryzae:12.5 μg/ml, Xanthomonas citri:(MIC)0.4 μg/ml, Xanthomonas citri:0.4 μg/ml(MIC), Xanthomonas oryzae:12.5 μg/ml(MIC), Mycobacterium phlei:12.5 μg/ml(MIC) |
体外活性 |
Ascamycin has a selective antibacterial activity against Xanthomonas species and it has C2-chloroadenine as the base on C-1' which lacks the chlorine.[1] Xanthomonas citri is susceptible to Ascamycin by virtue of the Ascamycin-dealanylating enzyme on the cell surface, When Ascamycin is dealanylated, Dealanylascamycin shows a broad antibacterial activity against various Gram-negative and Gram-positive bacteria.[2] |
分子量 | 451.84 |
分子式 | C13H18ClN7O7S |
CAS No. | 91432-48-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (22.13 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.2132 mL | 11.0659 mL | 22.1317 mL | 55.3293 mL |
5 mM | 0.4426 mL | 2.2132 mL | 4.4263 mL | 11.0659 mL | |
10 mM | 0.2213 mL | 1.1066 mL | 2.2132 mL | 5.5329 mL | |
20 mM | 0.1107 mL | 0.5533 mL | 1.1066 mL | 2.7665 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Ascamycin 91432-48-3 Cell Cycle/Checkpoint DNA Damage/DNA Repair Microbiology/Virology Others Nucleoside Antimetabolite/Analog Antibacterial Antibiotic Inhibitor inhibitor inhibit