Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Galocitabine (Neofrutulon) 是一种胸苷酸合成酶抑制剂,可能用于治疗癌症。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 2,300 | 现货 | ||
5 mg | ¥ 5,570 | 现货 | ||
10 mg | ¥ 7,790 | 现货 | ||
25 mg | ¥ 11,500 | 现货 | ||
50 mg | ¥ 15,600 | 现货 | ||
100 mg | ¥ 20,800 | 现货 |
产品描述 | Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer. |
体内活性 | We performed 4-week toxicity studies of capecitabine (N(4)-pentyloxycarbonyl-5'-deoxy-5-fluorouridine), galocitabine (trimethoxybenzyl-5'-deoxy-5-fluorocytidine), 4 different fluoropyrimidine carbamate analogs. Four-week toxicity data for capecitabine in rats and mice were also obtained for comparison. Capecitabine, galocitabine, butyl, and isopentyl analogs showed similar toxicities in hematopoietic and intestinal organs at 1.0 mmol/kg. These compounds showed slight toxicity at 0.5 mmol/kg and no toxicity at 0.1 mmol/kg. [1] |
别名 | RO 091390, RO-091390, RO091390, RO-09-1390, Neofrutulon |
分子量 | 439.39 |
分子式 | C19H22FN3O8 |
CAS No. | 124012-42-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (113.79 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.2759 mL | 11.3794 mL | 22.7588 mL | 56.8971 mL |
5 mM | 0.4552 mL | 2.2759 mL | 4.5518 mL | 11.3794 mL | |
10 mM | 0.2276 mL | 1.1379 mL | 2.2759 mL | 5.6897 mL | |
20 mM | 0.1138 mL | 0.569 mL | 1.1379 mL | 2.8449 mL | |
50 mM | 0.0455 mL | 0.2276 mL | 0.4552 mL | 1.1379 mL | |
100 mM | 0.0228 mL | 0.1138 mL | 0.2276 mL | 0.569 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Galocitabine 124012-42-6 Others RO 091390 RO-091390 RO091390 RO-09-1390 Neofrutulon Inhibitor inhibitor inhibit