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- 3550个临床期化合物集合，可用于高通量筛选和高内涵筛选；
- 所有化合物均已被批准进入临床期，按临床一期、二期、三期等进行分类；
- 是老药新用和细胞诱导的有效工具
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- 结构多样，药效显著，可渗透细胞；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
临床期小分子药物库
Clinical Compound Library
很棒临床期小分子药物库汇集了3550 个已经进入临床实验的化合物，这些化合物经过大量的临床前研究实验，具有活性高、毒性低和机制明确的特点。我们随货信息中每个化合物都包含了其作用靶点、临床期、适应症等信息，涉及癌症、炎症、感染、神经病、心血管病和消化系统疾病等多种热门病症，以及JAK、EGFR、mTOR、CDK、HDAC、AKt、PARP 等众多成药靶点，适用于药物筛选的同时，也是细胞诱导分化的有力工具。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
Excel
SDF
联系我们获取更多批次信息产品编号 L3400
临床期小分子药物库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
- 本化合物库通常以 DMSO 10 mM 浓度提供。少量产品可能因溶解性或稳定性需求，采用其他溶剂或浓度包装，具体以实际产品信息为准。
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化合物库组成
Autophagy
Apoptosis
Antibacterial
Antibiotic
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
DNA/RNA Synthesis
AChR
HIV Protease
Dopamine Receptor
COX
Histamine Receptor
VEGFR
Sodium Channel
Parasite
Potassium Channel
EGFR
Calcium Channel
PDE
PI3K
Antifungal
Topoisomerase
CDK
FLT
HCV Protease
Cytochromes P450
Dehydrogenase
PDGFR
SARS-CoV
JAK
FGFR
Microtubule Associated
PPAR
c-Kit
Glucocorticoid Receptor
Reactive Oxygen Species
Ferroptosis
HDAC
Influenza Virus
c-Met/HGFR
mTOR
GABA Receptor
Src
Estrogen/progestogen Receptor
HBV
NF-κB
Mitophagy
Prostaglandin Receptor
RAAS
Reverse Transcriptase
Tyrosine Kinases
Adenosine Receptor
Nucleoside Antimetabolite/Analog
GPCR
Androgen Receptor
Raf
Bcr-Abl
iGluR
Proteasome
Epigenetic Reader Domain
NMDAR
Serotonin Transporter
GluR
Phosphatase
Akt
HSV
PARP
ROS
TRP/TRPV Channel
Virus Protease
Beta Amyloid
Transferase
Aurora Kinase
Estrogen Receptor/ERR
HSP
Norepinephrine
p38 MAPK
ALK
HIF/HIF Prolyl-Hydroxylase
MEK
Progesterone Receptor
Antiviral
ATPase
c-RET
IL Receptor
Opioid Receptor
TNF
Antioxidant
Cholinesterase (ChE)
DPP-4
HER
Histone Methyltransferase
P-gp
Antifection
Carbonic Anhydrase
ribosome
TLR
Trk receptor
c-Fms
CXCR
Endothelin Receptor
ERK
GSK-3
MMP
PKC
CCR
Chk
DNA Alkylator/Crosslinker
Interleukin
MAO
Retinoid Receptor
S1P Receptor
TAM Receptor
Thrombin
AMPK
Bcl-2 Family
E1/E2/E3 Enzyme
Gamma-secretase
Mitochondrial Metabolism
p53
Syk
Caspase
CFTR
DNA-PK
HIF
Integrin
LPL Receptor
Phospholipase
Proton pump
SGLT
STAT
Thyroid hormone receptor(THR)
Wnt/beta-catenin
Antifolate
FAK
Guanylate cyclase
NO Synthase
Nrf2
CSF-1R
DNA Alkylation
Hedgehog/Smoothened
NADPH
Neurokinin receptor
P2X Receptor
PLK
BTK
ATM/ATR
Cannabinoid Receptor
CETP
DHFR
Glutathione Peroxidase
HMG-CoA Reductase
Hydroxylase
IAP
IGF-1R
Lipoxygenase
MRP
OX Receptor
P2Y Receptor
Reductase
ROCK
ROS Kinase
RSV
S6 Kinase
TGF-beta/Smad
Vasopressin Receptor
GNRH Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Mdm2
Monoamine Oxidase
PKA
ADC Cytotoxin
Aminopeptidase
Aryl Hydrocarbon Receptor
Beta-Secretase
Casein Kinase
DNA
DNA Methyltransferase
Drug Metabolite
Factor Xa
FXR
Glucosidase
Histone Demethylase
Kinesin
Ligand for E3 Ligase
Pim
RIP kinase
Serine Protease
Sigma receptor
Sirtuin
Smo
Xanthine Oxidase
AhR
Amino Acids and Derivatives
BACE
Bradykinin Receptor
Glucagon Receptor
Glucokinase
IRAK
Isocitrate Dehydrogenase (IDH)
IκB/IKK
JNK
PAK
ROR
Acyltransferase
Complement System
CRFR
Ephrin Receptor
Fatty Acid Synthase
Gap Junction Protein
GHSR
IDO
Leukotriene Receptor
Molecular Glues
MT Receptor
NOS
Ras
Acetyl-CoA Carboxylase
CaMK
CGRP Receptor
Chloride channel
Cholecystokinin Receptor
CRM1
Cysteine Protease
Decarboxylase
DNA gyrase
DprE1
FAAH
GlyT
IFNAR
Liver X Receptor
LTR
MAPK
Melanocortin Receptor
Melatonin Receptor
Monoamine Transporter
NADPH-oxidase
Neprilysin
Neuropeptide Y Receptor
OAT
PGE Synthase
PROTACs
Tie-2
Wee1
YAP
Kras
ABC Transporter
Adenosine Deaminase
Annexin A
Arginase
CaSR
Cell wall
DUB
Free radical scavengers
Glutaminase
GPCR19
Imidazoline Receptor
KSP
LPA Receptor
Myosin
NAMPT
NEDD8
NOD
NOD-like Receptor (NLR)
PD-1/PD-L1
PDK
PERK
Protease-activated Receptor
PYK2
Rho
Somatostatin
STING
Telomerase
Tyrosinase
UGT
ATP Citrate Lyase
BCRP
CD73
c-Myc
Discoidin Domain Receptor (DDR)
DYRK
Epoxide Hydrolase
Galectin
GSNOR
GST
HCN Channel
Hexokinase
Integrase
IRE1
LDL
Ligands for Target Protein for PROTAC
MLK
Na-K-Cl cotransporter
Oxytocin Receptor
p97
PAI-1
Porcupine
Serine/threonin kinase
Stearoyl-CoA Desaturase (SCD)
Taste receptor
transporter
VDA
AAK1
ACK1
Adenylyl Cyclase
Advanced Glycation End Products
Anion Exchanger
Anti-infection
Apelin receptor
Aquaporin
Aromatase
Arrestin
ASK
BMI-1
CRISPR/Cas9
Fas/FasL
FLAP
GluCls
GRK
GTPase
Hck
Hippo pathway
Histone Acetyltransferase
Huntingtin
Hydrogenase
KLF
Lipase
Lipid
MALT
MELK
Methionine Adenosyltransferase (MAT)
MicroRNA
MNK
Monocarboxylate transporter
N-Acetylglucosaminyltransferase
Neurotensin Receptor
NPC1L1
PAFR
Phosphorylase
PI4K
PKM
PROTAC Linker
PSMA
Pyroptosis
RXFP receptor
SGK
SIK
Stemness kinase
Survivin
Thioredoxin
TOPK
VDAC
Drug-Linker Conjugates for ADC
Vitamin
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