Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hydrocortisone cypionate is a corticosteroid ester and synthetic glucocorticoid corticosteroid.
产品描述 | Hydrocortisone cypionate is a corticosteroid ester and synthetic glucocorticoid corticosteroid. |
体外活性 | Hydrocortisone-treated DCs inhibit production of IFN-γ but induce an increased release of IL-4 and no change in IL-5.?Hydrocortisone reduces postischemic oxidative stress, perfusion pressure, and transudate formation.?Hydrocortisone inhibits postischemic shedding of syndecan-1, heparan sulfate, and hyaluronan as is release of histamine from resident mast cells.Hydrocortisone (50 nM) shows a dose-dependent down-regulation of GR transcript in hCMEC/D3 cells. Hydrocortisone supplementation of the serum-reduced cell differentiation medium leads to a significant increase in TER across the hCMEC/D3 monolayer. Hydrocortisone-treated Dendritic cells (DCs) show a decreased expression of MHC II molecules, the costimulatory molecule CD86, and the DC-specific marker CD83, as well as a strongly reduced IL-12 secretion. |
分子量 | 486.64 |
分子式 | C29H42O6 |
CAS No. | 508-99-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (256.86 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.0549 mL | 10.2745 mL | 20.5491 mL | 51.3727 mL |
5 mM | 0.411 mL | 2.0549 mL | 4.1098 mL | 10.2745 mL | |
10 mM | 0.2055 mL | 1.0275 mL | 2.0549 mL | 5.1373 mL | |
20 mM | 0.1027 mL | 0.5137 mL | 1.0275 mL | 2.5686 mL | |
50 mM | 0.0411 mL | 0.2055 mL | 0.411 mL | 1.0275 mL | |
100 mM | 0.0205 mL | 0.1027 mL | 0.2055 mL | 0.5137 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Hydrocortisone cypionate 508-99-6 Others Inhibitor inhibitor inhibit