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Anti-ADGRE1 Antibody (6G833) 是一种 Mouse 抗体,靶向 ADGRE1。Anti-ADGRE1 Antibody (6G833) 可用于 WB。
Anti-ADGRE1 Antibody (6G833) 是一种 Mouse 抗体,靶向 ADGRE1。Anti-ADGRE1 Antibody (6G833) 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,165 | 5日内发货 | |
100 μL | ¥ 1,965 | 5日内发货 |
产品描述 | Anti-ADGRE1 Antibody (6G833) is a Mouse antibody targeting ADGRE1. Anti-ADGRE1 Antibody (6G833) can be used in WB. |
Ig Type | IgG |
克隆号 | 6G833 |
交叉反应 | Human (predicted:Mouse,Rat) |
验证活性 | Sample: Lane 1: Human HL-60 cell lysates Primary: Anti-ADGRE1 (F4/80) (TMAB-00062) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 95 kDa Observed band size: 120 kDa |
应用 | |
推荐剂量 | WB: 1:100-1000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
亚细胞定位 | Cell membrane. |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Protein G purified |
性状 | Liquid |
缓冲液 | 0.01M PBS (pH7.4) with 0.1% BSA, 0.02% Proclin300. |
研究背景 | The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages. |
免疫原 | KLH conjugated synthetic peptide: mouse F4/80 |
抗原种属 | Mouse |
基因ID | |
Uniprot ID | |
研究领域 | Macrophage / Inflamm.,Other Cell Types |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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