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Anti-ADGRE1 Antibody (6G833)
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产品编号 TMAB-00062
别名 TM7LN3, Lymphocyte antigen 71, Ly71, Gpf480, F4/80, EMR1 hormone receptor, EMR1, EMR 1, EGFTM7, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, EGF TM7, EGF like module receptor 1, Egf like module containing mucin like hormone receptor like sequence 1, Egf like module containing mucin like hormone receptor like 1, DD7A5 7, Cell surface glycoprotein F4/80, Cell surface glycoprotein EMR1, AGRE1, Adhesion G protein-coupled receptor E1
Anti-ADGRE1 Antibody (6G833) 是一种 Mouse 抗体，靶向 ADGRE1。Anti-ADGRE1 Antibody (6G833) 可用于 WB。
Anti-ADGRE1 Antibody (6G833)
Anti-ADGRE1 Antibody (6G833)
还可以产品编号 TMAB-00062 别名 TM7LN3, Lymphocyte antigen 71, Ly71, Gpf480, F4/80, EMR1 hormone receptor, EMR1, EMR 1, EGFTM7, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, EGF TM7, EGF like module receptor 1, Egf like module containing mucin like hormone receptor like sequence 1, Egf like module containing mucin like hormone receptor like 1, DD7A5 7, Cell surface glycoprotein F4/80, Cell surface glycoprotein EMR1, AGRE1, Adhesion G protein-coupled receptor E1
Anti-ADGRE1 Antibody (6G833) 是一种 Mouse 抗体，靶向 ADGRE1。Anti-ADGRE1 Antibody (6G833) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 |
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产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-ADGRE1 Antibody (6G833) is a Mouse antibody targeting ADGRE1. Anti-ADGRE1 Antibody (6G833) can be used in WB. |
| 疾病造模方案 | |
| 别名 | TM7LN3, Lymphocyte antigen 71, Ly71, Gpf480, F4/80, EMR1 hormone receptor, EMR1, EMR 1, EGFTM7, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, EGF TM7, EGF like module receptor 1, Egf like module containing mucin like hormone receptor like sequence 1, Egf like module containing mucin like hormone receptor like 1, DD7A5 7, Cell surface glycoprotein F4/80, Cell surface glycoprotein EMR1, AGRE1, Adhesion G protein-coupled receptor E1 |
| Ig Type | IgG |
| 克隆号 | 6G833 |
| 交叉反应 | Human (predicted:Mouse,Rat) |
| 验证活性 | Sample: Lane 1: Human HL-60 cell lysates Primary: Anti-ADGRE1 (F4/80) (TMAB-00062) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 95 kDa Observed band size: 120 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:100-1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Wide expression; increased levels in peripheral blood mononuclear cells. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M PBS (pH7.4) with 0.1% BSA, 0.02% Proclin300. |
| 浓度 | 200 μg/ml |
| 研究背景 | The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages. |
| 免疫原 | KLH conjugated synthetic peptide: mouse F4/80 |
| 抗原种属 | Mouse |
| 基因名称 | ADGRE1 |
| 基因ID | |
| 蛋白名称 | Adhesion G protein-coupled receptor E1 |
| Uniprot ID | |
| 研究领域 | Macrophage / Inflamm.,Other Cell Types |
| 功能 | Could be involved in cell-cell interactions. |
| 分子量 | Theoretical: 95 kDa. Actual: 100-100 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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