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Anti-ADGRE1 Antibody (6G833)

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Anti-ADGRE1 Antibody (6G833)
产品编号 TMAB-00062

Anti-ADGRE1 Antibody (6G833) 是一种 Mouse 抗体,靶向 ADGRE1。Anti-ADGRE1 Antibody (6G833) 可用于 WB。

Anti-ADGRE1 Antibody (6G833)

Anti-ADGRE1 Antibody (6G833)

Rating icon 还可以
Anti-ADGRE1 Antibody (6G833)
产品编号 TMAB-00062

Anti-ADGRE1 Antibody (6G833) 是一种 Mouse 抗体,靶向 ADGRE1。Anti-ADGRE1 Antibody (6G833) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADGRE1 Antibody (6G833) is a Mouse antibody targeting ADGRE1. Anti-ADGRE1 Antibody (6G833) can be used in WB.
Ig Type
IgG
克隆号
6G833
交叉反应
Human (predicted:Mouse,Rat)
验证活性
Sample:
Lane 1: Human HL-60 cell lysates
Primary: Anti-ADGRE1 (F4/80) (TMAB-00062) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 95 kDa
Observed band size: 120 kDa
应用
推荐剂量
WB: 1:100-1000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell membrane.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M PBS (pH7.4) with 0.1% BSA, 0.02% Proclin300.
研究背景The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse F4/80
抗原种属
Mouse
基因ID
Uniprot ID
研究领域
Macrophage / Inflamm.,Other Cell Types
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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