Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T80544 | PTPσ Inhibitor, ISP
化合物 PTPσ Inhibitor, ISP
|
98% |
|
|
PTPσ Inhibitor, ISP 结合并抑制重组人PTPσ的信号传导,具有穿透细胞膜的能力,有助于缓解CSPG介导的脊髓损伤模型中轴突的生长抑制。该抑制剂能增强LPC引起的脊髓脱髓鞘损伤的髓鞘再生,并在MS动物模型中促进OPC的迁移、分化、髓鞘形成及功能恢复。 | ||||
T80571 | Eurestobart
化合物 Eurestobart
|
2682847-53-4 | 98% |
Eurestobart
|
Eurestobart为人源化IgG1κ抗体,专一性靶向ENTPDase。 | ||||
TN2887 | 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid
化合物 TN2887
|
329975-47-5 | 98% |
|
(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM. | ||||
T3930 | Taraxerol acetate
醋酸蒲公英霜
|
2189-80-2 | 98% |
|
Taraxeryl acetate shows the significant antiviral activity against herpes simplex virus (type II). It has less effect on cell cycle arrest and apoptosis of AGS c... | ||||
TN3525 | Boehmenan
化合物 TN3525
|
57296-22-7 | 98% |
|
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ... | ||||
T11687 | Itacitinib adipate
化合物 T11687
|
1334302-63-4 | 98% |
|
Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor,Itacitinib adipate has been tested for efficacy and safety in a phase II trial in myelo... | ||||
TN3335 | Abyssinone V
化合物Abyssinone V
|
77263-11-7 | 98% |
|
Abyssinone V 是一种从刺桐茎皮中分离的天然化合物,是蛋白质酪氨酸磷酸酶 1B (PTP1B) 的抑制剂。 | ||||
T14037 | 3α-Aminocholestane
3α-氨基胆甾烷
|
2206-20-4 | 98% |
|
3α-Aminocholestane (5α-Cholestan-3α-amine) 是包含 SH2 结构域的肌醇-5'-磷酸酶 1 (SHIP1) 的有效抑制剂(IC50 : 2.5 μM),可用于研究和免疫相关的疾病。 | ||||
T11735 | K-Ras G12C-IN-1
化合物 T11735
|
1629265-17-3 | 98% |
|
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C. | ||||
T12934 | SMAP-2
化合物 T12934
|
1809068-70-9 | 98% |
|
SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhib... | ||||
TN4551 | Methyl orsellinate
化合物 TN4551
|
3187-58-4 | 98% |
|
Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus... | ||||
T15243 | Ertiprotafib
化合物 T15243
|
251303-04-5 | 98% |
|
Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPA... | ||||
TN4064 | Flavoglaucin
化合物 TN4064
|
523-73-9 | 98% |
|
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab... | ||||
T60396 | JMS-053
化合物 JMS-053
|
1954650-11-3 | 98% |
|
JMS-053 是一种具有有效性和选择性的磷酸酶 DUSP3 抑制剂, 抑制 PTP4A3、 PTP4A1 、 PTP4A2 和 CDC25B,抑制癌细胞迁移和球体生长,避免血管内皮生长因子或脂多糖对微血管内皮屏障功能的破坏。 | ||||
T15166 | DPM-1001
化合物 T15166
|
1471172-27-6 | 98% |
|
DPM-1001 is an orally bioavailable and non-competitive protein-tyrosine phosphatase (PTP1B) inhibitor (IC50: 100 nM) with the anti-diabetic property. | ||||
T16517 | PGMI-004A
化合物PGMI-004A
|
1313738-90-7 | 98% |
|
PGMI-004A 是磷酸甘油酸变位酶 1 抑制剂,IC50=13.1 μM。 | ||||
TN3505 | Beta-Peltoboykinolic acid
化合物 TN3505
|
24778-48-1 | 98% |
|
Beta-Peltoboykinolic acid has in vitro protein tyrosine phosphatase 1B (PTP1B) inhibitory, it inhibits PTP1B with IC50 values of 5.2+/-0.5 microM. It also has cy... | ||||
T10060L | DT-061
化合物 T10060L
|
1809427-19-7 | 98% |
|
DT-061 is an orally bioavailable protein phosphatase 2A (PP2A) activator. It could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis. | ||||
TN2913 | 3-Acetoxy-11-ursen-28,13-olide
化合物 TN2913
|
35959-08-1 | 98% |
|
3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. It exhibit... | ||||
T35806 | N-Stearoylsphingosine
N-硬脂酰神经鞘氨醇
|
2304-81-6 | 98% |
|
N-Stearoylsphingosine (Cer(d18:1/18:0)) 是一种广泛存在真核生物体内的酰胺类化合物,通过干扰PP2A与PP2A抑制剂2的结合来增强蛋白质磷酸酶2A(PP2A)活性,导致Akt去磷酸化。N-Stearoylsphingosine 可用于研究前列腺癌。 |