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LRRK2

Leucine-rich repeat kinase 2 (LRRK2), also known as dardarin (from the Basque word "dardara" which means trembling) and PARK8 (from early identified association with Parkinson's disease), is a kinase enzyme that in humans is encoded by the LRRK2 gene. LRRK2 is a member of the leucine-rich repeat kinase family. Variants of this gene are associated with an increased risk of Parkinson's disease and also Crohn's disease.

Cat. No.	Product Name	CAS No.	Purity
T5428	BIX 02565 化合物BIX 02565	1311367-27-7	98%
T5428	BIX 02565 是核糖体 S6 激酶 2 (RSK2) 抑制剂，IC50为 1.1 nM。
T39972	EB-42486 化合物EB-42486	2390475-81-5	98%
T39972	EB-42486 是一种有效且高度选择性的 G2019S-LRRK2 抑制剂，IC50 < 0.2 nM。
T6057	URMC-099 化合物URMC099	1229582-33-5	98%
T6057	URMC-099 是一种具有优异的血脑屏障穿透性的，可口服的混合谱系激酶 3 抑制剂，IC50为14 nM。