Akt

Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.

Cat. No.	Product Name	CAS No.	Purity
TN4038	Eupatolide 泽兰内酯	6750-25-0	98%
TN4038	Eupatolide 是从 Inula japonica 的花中分离出来的，具有抗炎活性。 Eupatolide 可用于研究乳腺癌细胞对 TRAIL 的耐药性。
T10274	AKT-IN-2 化合物 T10274	1295514-91-8	98%
T10274	AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
T11743	Kanosamine hydrochloride 化合物 T11743	57649-10-2	98%
T11743	Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species. Kanosamine inhibits...
TN4263	Isoangustone A 化合物 TN4263	129280-34-8	98%
TN4263	Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ...
TN4390	Kihadanin B 化合物 TN4390	73793-68-7	98%
TN4390	Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.
TN1376	α-Solanine α-茄碱	20562-02-1	98%
TN1376	Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
TN1235	3,4,5-Tricaffeoylquinic acid 3,4,5-三咖啡酰奎宁酸	86632-03-3	98%
TN1235	3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like rece...
TN3691	Communic acid 化合物 TN3691	2761-77-5	98%
TN3691	Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
TN3525	Boehmenan 化合物 TN3525	57296-22-7	98%
TN3525	(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ...
TN3219	7,8-Didehydrocimigenol 化合物 TN3219	150972-72-8	98%
TN3219	7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of ...
TN1458	Buddlejasaponin IV 醉鱼草皂苷 Ⅳ	139523-30-1	98%
TN1458	Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-ka...
TN4244	Icariside B1 淫羊藿次甙B1	109062-00-2	98%
TN4244	Icariside B1 shows inhibitory effects on LPS-induced NO production in RAW264.7 cells.
TN1889	Lupalbigenin 化合物Lupalbigenin	76754-24-0	98%
TN1889	Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
TN4506	(+)-Matairesinol 化合物 TN4506	148409-36-3	98%
TN4506	(+)-Matairesinol exhibits immunomodulatory activity; it also shows inhibition of the discoloration of yellowtail dark muscle.
TN3139	5α-Hydroxycostic acid 化合物 TN3139	132185-83-2	98%
TN3139	5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate.
T15056	DB07107 化合物 T15056	552332-71-5	98%
T15056	DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).
T2S0606	Bakkenolide A 蜂斗菜内酯A	19906-72-0	98%
T2S0606	Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
TMA1743	Ergosterol peroxide 过氧麦角甾醇	2061-64-5	98%
TMA1743	Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
TN2328	Zeylenone 山椒子烯酮	193410-84-3	98%
TN2328	Zeylenone 是一种来自 Uvaria grandiflora的环己烯氧化物，具有抗肿瘤和抗癌细胞增殖活性，通过 PI3K/AKT/mTOR 和 MAPK/ERK 信号通路抑制宫颈癌细胞增殖，诱导细胞凋亡 (apoptosis)。
T75078	Antitumor agent-86 化合物 Antitumor agent-86	2907704-65-6	98%
T75078	Antitumor agent-86 (compound 5a) 对MCF-7乳腺癌细胞线具有IC50值2.62 µM的抑制活性。该化合物通过促进细胞凋亡和引发细胞周期阻滞来表现其抗癌效能，并对RAS/PI3K/Akt/JNK信号传导途径具有靶向作用。