AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.

Cat. No.	Product Name	CAS No.	Purity
TN2217	Sophoflavescenol 槐苦参醇	216450-65-6	99.65%
TN2217	Sophoflavescenol 是异戊烯基黄酮类化合物，能够抑制PDE5的活性，IC50=0.013 μM。它也抑制 RLAR，HRAR，BACE1，AChE 和 BChE，IC50值分别为 0.30 µM，0.17 µM，10.98 µM，8.37 µM 和 8.21 µM。
TN1798	Isorosmanol 异迷迭香酚	93780-80-4	98.85%
TN1798	Isorosmanol 具有抗氧化、神经保护和神经营养作用，可能用于老年性疾病，如认知功能下降和色素沉着。
T0346	Camylofine 卡米罗芬	54-30-8	98%
T0346	Camylofine (Avacan) 是抗胆碱剂，也是一种平滑肌松弛剂。
TN1519	(S)-Coclaurine 化合物Coclaurine	486-39-5	97.72%
TN1519	(S)-Coclaurine (Coclaurine) 是一种从 Sarcopetalum harveyanum 中分离出来的，是一种 nAChR 拮抗剂。
T68019	Ursulcholic acid 熊硫胆酸	88426-32-8	100%
T68019	Ursulcholic acid (Ursulcholic) 是一种可溶于水的抗胆碱能化合物。
T1236	Pentolinium Tartrate 酒石酸喷托铵	52-62-0
T1236	Pentolinium Tartrate (Pendine) 是烟碱拮抗剂，已被用作高血压的神经节阻滞剂。
T0218	Biperiden 比哌立登	514-65-8
T0218	Biperiden (Bipariden) 是中枢 M1胆碱受体阻断剂，有抗帕金森症活性。
T13129	Terodiline hydrochloride 盐酸特罗地林	7082-21-5	98%
T13129	Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bl...
T6721	Vinblastine 长春质碱	865-21-4	98%
T6721	Vinblastine 抑制微管形成并抑制 nAChR 活性，IC50 为 8.9 μM，用于治疗某些类型的癌症。
TN4837	Pseudotaraxasterol 化合物 TN4837	464-98-2	98%
TN4837	Pseudotaraxasterol shows cytotoxic activity against MOLT-4 cells.
TN3696	Conodurine 化合物 TN3696	2665-57-8	98%
TN3696	Conodurine shows leishmanicidal and antibacterial activities, it shows inhibition activity for acetyl (AChE) and butyrylcholinesterase (BuChE).
TN1559	Dehydrodicentrine 去氢荷包牡丹碱	19843-03-9	98%
TN1559	Dehydrodicentrine showed strong acetylcholinesterase (AChE) inhibitory effects with the IC50 value of 2.98 μM.
T12020	Metixene hydrochloride 盐酸麦塞散	1553-34-0	98%
T12020	Metixene hydrochloride is an anticholinergic antiparkinsonian agent.
TN1645	Flavokawain C 2',4-二羟基-4',6'-二甲氧基查耳酮	56798-34-6	98%
TN1645	Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 μM. Flavokawain C has anti-tumor activity, it inhibited cell cycle...
TN1653	Fustin 黄颜木素	20725-03-5	98%
TN1653	Fustin 是植物漆树 (Rhus verniciflua Stokes) 的植物性黄烷醇成分。 Fustin 对 6-羟基多巴胺诱导的神经元细胞死亡具有保护作用。
TN3380	Alloisoimperatorin 化合物 TN3380	35214-83-6	98%
TN3380	Alloisoimperatorin is a candidate of AChE inhibitors, it displays potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by...
T13713	GP531 化合物 T13713	142344-87-4	98%
T13713	GP531 is a second-generation adenosine regulating agent. It is pharmacologically silent under basal conditions but increases localized endogenous adenosine durin...
TN2505	1,5-Diphenylpentan-1-one 化合物 TN2505	39686-51-6	98%
TN2505	1,5-Diphenylpentan-1-one shows poor insecticidal and acetylcholinesterase inhibitory activities.
TN4652	Niazimicin 化合物 TN4652	147821-49-6	98%
TN4652	Niazimicin are NF-B and PI3K inhibitors, which shows antimicrobial, hypotensive and spasmolytic activities. Niazimicin has potent antitumor promoting activity in...
TN1848	Kuwanon E 桑皮酮 E	68401-05-8	98%
TN1848	Kuwanon E inhibited cholinesterase enzyme in a dose-dependent manner with K i values ranging between 3.1 and 37.5 μM and between 1.7 and 19.1 μM against acetylch...