prostaglandin d1

Prostaglandin D1 是对离体人动脉具有收缩和舒张作用的一种前列腺素，能抑制 ADP 诱导的血小板聚集（ IC50=320 ng/ml）。Prostaglandin D1 可用于代谢研究。

Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2. 13,14-dihydro-15-keto Prostaglandin D1 (13,14-dihydro-15-keto PGD1) is the theoretical metabolite of PGD1 via the 15-hydroxy PG dehydrogenase metabolic pathway. No biological studies for this compound have been reported.