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Search Results for " monophosphate "

114

抑制剂 & 化合物

36

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T21195	AICAR monophosphate Aica ribonucleotide,AICA riboside,Acadesine 5'-monophosphate,Z-nucleotide	Others	Others
	AICAR monophosphate (Aica ribonucleotide) 是一种具有抗肿瘤活性的嘌呤前体，可用于 2 型糖尿病的研究。
T37636	2'-Deoxyguanosine 5'-monophosphate disodium 5′-dGMP disodium	Endogenous Metabolite	Metabolism
	2'-Deoxyguanosine 5'-monophosphate disodium (5'-dGMP disodium) 是一种核酸三磷酸鸟苷（GTP）衍生物，可作为可氧化靶标，可用于和其他化合物组成多元配合物。
T65979	Adenosine 5'-monophosphate disodium salt Adenosine Phosphate Disodium,5‘-AMP-NA2	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) 是一种参与 ATP 代谢的嘌呤核苷酸，用于研究 ATP 对细胞和生物体的影响。Adenosine 5'-monophosphate disodium salt 已被证明具有多种生化和生理作用,它可以促进细胞代谢、基因表达和蛋白质合成。
T21329	Gemcitabine monophosphate disodium salt Gemcitabine monophosphate disodium salt monohydrate,Gemcitabine monophosphate disodium,GemMP
	R306465 is a novel HDAC inhibitor with broad-spectrum antitumor activity against solid (IC50: 30 to 300 nM) and hematological malignancies. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro.
T68656	Brivudine monophosphate
	Brivudine monophosphate is a phosphate ester of Brivudine. Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator...
T71036	Adefovir monophosphate
	Adefovir monophosphate is an antiviral acyclic nucleoside phosphonate (ANP) analog with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV). It is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) that works by blocking reverse transcriptase for the treatment of hepatitis B. Adefovir dipivoxil is not effective against HIV-1.
T39334	Remdesivir nucleoside monophosphate
	Remdesivir nucleoside monophosphate, a metabolite of Remdesivir, is a potent antiviral compound with nucleoside analogue characteristics. It exhibits effective antiviral activity against both SARS-CoV and MERS-CoV.
T33099	Lyxoflavin 5'-monophosphate
	Lyxoflavin 5'-monophosphate binds to flavodoxin.
T37877	Ribavirin 5'-monophosphate (lithium salt)
	Ribavirin 5'-monophosphate (lithium salt)对 IMP 脱氢酶（将 IMP 转化为 XMP）具体直接抑制作用
T37375	Uridine-3'-monophosphate (sodium salt)
	Uridine-3'-monophosphate is a nucleoside used in the biochemical synthesis of ribothymidine-3'-phosphate. It has been used as a bioavailable source of uridine in research studies designed to enhance learning and memory.
T35652	2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
	2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.
T35571	Adenosine 3’-monophosphate (sodium salt hydrate)
	Adenosine 3’-monophosphate is a nucleotide and metabolite formedviahydrolysis of 2’,3’-cAMP by metal-dependent phosphodiesterases.1It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A2Breceptor antagonist MRS1754.2Adenosine 3’-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine .
T37789	Riboflavin 5'-monophosphate (sodium salt hydrate)
	Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalyzing oxidation and reduction reactions in a variety of biosynthetic pathways. FMN also binds the FMN riboswitch (RFN element) on RNA to alter gene regulation. FMN is a substrate of FMN phosphohydrolases and is used to study their function.
T36300	Uridine-5’-monophosphate (sodium salt hydrate)
	Uridine-5’-monophosphate (UMP) is a ribonucleotide.1It is formedviadecarboxylation of orotidine-5’-monophosphate (5’-OMP) by OMP decarboxylase. UMP is further phosphorylated by UMP-CMP kinase to form UDP and UTP during nucleic acid biosynthesis. Formulations containing UMP have been used as dietary supplements. 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Nucleotide BiosynthesisBiochemistry(2002)
T22825	Guanosine-2'(3')-monophosphate disodium salt
	Guanosine-2'(3')-monophosphate disodium salt 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T22825。
T4187	Gemcitabine monophosphate sodium salt hydrate	Others; DNA; DNA/RNA Synthesis; Autophagy	Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Gemcitabine monophosphate sodium salt hydrate 是Gemcitabine 的单磷酸盐衍生物。
T5166L	Leniolisib phosphate Leniolisib monophosphate
	Leniolisib phosphate is an effective PI3K inhibitor.
T22869	Inosine-5'-monophosphate (sodium salt hydrate)	Others	Others
	substrate of IMP dehydrogenase (IMPDH)
T12162	N6-Methyladenosine 5'-monophosphate disodium salt	Others	Others
	N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator(Ka of 22 µM).
T15339	Foscarbidopa Carbidopa 4′-monophosphate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Foscarbidopa is a prodrug of Carbidopa. It acts as a dopamine receptor agonist.
T60709	Acyclovir monophosphate
	Acyclovir monophosphate 是抗单纯疱疹病毒 (HSV)剂，并且具有抗肿瘤活性。Acyclovir monophosphate 通过抑制病毒 DNA 聚合酶从而阻断 DNA 合成，同时能终止病毒 DNA 的链延伸。
T1129	Benfotiamine Benzoylthiamine monophosphate,S-Benzoylthiamine O-monophosphate,苯磷硫胺	Others	Others
	Benfotiamine (S-Benzoylthiamine O-monophosphate) 是维生素 B1 的类似物，其吸收率和生物利用度比维生素B1高，具有直接抗氧化能力，可防止DNA 损伤。它常用作糖尿病并发症的食品补充剂。
T75377	Thymolphthalein monophosphate disodium hydrate
	Thymolphthalein monophosphate disodium hydrate 是用于测定酸性及碱性磷酸酶显色底物。反应过程中释放的百里酚酞可增加介质pH，促使颜色产生并终止水解作用，特别适合于血清中前列腺磷酸酶的特异性检测。
T39890	8-Bromo-AMP 8-Bromoadenosine 5'-monophosphate,8-Bromo-AMP,8-Bromoadenylicacid
	8-Bromo-AMP, also known as 8-Bromoadenosine 5'-monophosphate, is a membrane permeable cAMP analogue. It enhances cardiac recovery from ischemia and reperfusion by elevating ATP, ADP, and total adenine nucleotide concentrations.
T77247	D-myo-Inositol 4-monophosphate
	D-myo-Inositol 4-mono-phos-phate 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。
TNU1647	Adenosine 5’-monophosphate triethylammonium salt
	Adenosine 5’-monophosphate triethylammonium salt 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1647。
T67245	Inosine-5'-monophosphate Disodium Salt heptahydrate
	Inosine-5'-monophosphate Disodium Salt heptahydrate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67245，CAS号为 849725-39-9。
T83472	1,N6-Ethenoadenosine 5'-monophosphate sodium 1,N6-ε-AMP sodium,1,N6-Etheno-AMP sodium
	1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium 是一种针对adenosine 5'-monophosphate系统的荧光探针，具备低浓度检测能力。该化合物拥有较长的激发波长（250-300 nm）和415 nm的发射波长。
TNU1275	2’-O-Methyladenosine 5’-monophosphate triethyl ammonium
	Nucleoside Phosphates; Nucleoside Derivateives - 2’-Modified nucleosides
T75195	2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethylammonium
	2’-Deoxy-2’-fluoroadenosine 5’-monophosphate (triethylammonium) 是嘌呤核苷类似物，主要应用于靶向惰性淋巴系统恶性肿瘤的抗肿瘤活性研究中。其抗癌机制包括抑制 DNA 合成和诱导细胞凋亡 (apoptosis)，显示出广泛的抗肿瘤效果。
T75198	2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethylammonium
	2’-O,4’-C-Methyleneadenosine 5’-monophosphate (triethylammonium) 是一种具有广泛抗肿瘤活性的嘌呤核苷类似物，主要针对惰性淋巴系统的恶性肿瘤。其作用机制涉及抑制 DNA 合成和诱导细胞凋亡(apoptosis)。
T75196	2’-O-Methyladenosine 5’-monophosphate triethyl ammonium
	2’-O-Methyladenosine 5’-monophosphate triethyl ammonium 是一种腺嘌呤核苷类似物。腺苷类似物大多可作为平滑肌血管扩张剂，也被证明能够抑制癌症进展。它的热门产品有 Adenosine phosphate，Acadesine ，Clofarabine ，Fludarabine phosphate 和 Vidarabine 。
T75197	2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium
	2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium 是一种嘌呤核苷类似物，拥有广泛的抗肿瘤活性，特别是对惰性淋巴系统的恶性肿瘤。其抗癌作用机制主要通过抑制 DNA 合成及诱导细胞凋亡（apoptosis）实现。
TNU1259	2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium
	Nucleoside Phosphates;
TNU1276	2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium
	2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1276。
T75188	2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium
	2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium 为嘌呤核苷类似物，主要拥有广泛的抗肿瘤活性，并针对惰性淋巴系统恶性肿瘤。其抗癌作用机制涉及抑制 DNA 合成和诱导细胞凋亡(apoptosis)等过程。
TNU1274	2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium
	Nucleoside Phosphates; Nucleoside Derivateives - 2’-Modified nucleosides; Fluoro-modified nucleosides
T7447	Adefovir	HBV; Reverse Transcriptase; Telomerase	DNA Damage/DNA Repair; Microbiology/Virology
	Adefovir 是一种单磷酸腺苷类似物抗病毒剂，在细胞内转化为 Adefovir diphosphate 后可抑制HBVDNA 聚合酶。它在 HepG2.2.15 细胞系中对HBV 的IC50为 0.7 μM。它对多种病毒(包括HBV 和疱疹病毒)具有良好的抗病毒活性。
TNU1277	2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium
	2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1277。
T33762	Fosifloxuridine nafalbenamide NUC-3373,NUC3373,NUC 3373	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Fosifloxuridine nafalbenamide (NUC 3373) 是一种胸腺嘧啶合酶抑制剂，属于嘧啶核苷酸类似物，具有抗癌活性。它能诱发宿主免疫反应，有潜力增强免疫治疗。
TNU1630	2’-O-Methyl-N6-methyladenosine 5’-monophosphate triethylammonium salt (60091-05-6 neutral molecule)
	2’-O-Methyl-N6-methyladenosine 5’-monophosphate triethylammonium salt (60091-05-6 neutral molecule) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1630。
T35421	2'-O-Succinyl-cAMP
	2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2
T20048	Vidarabine phosphate	Antiviral	Immunology/Inflammation
	Vidarabine phosphate 是一种单磷酸腺苷类似物。它是 VIDARABINE 的单磷酸酯。它还具有抗病毒和可能的抗肿瘤特性。
T8735	Sulbactum Sodium 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸	Others	Others
	Sulbactum Sodium (5'-CDP) 由胞苷一磷酸 (CMP) 或尿苷一磷酸 (UMP) 通过磷酸基团的转移在尿苷酸激酶 (UMPK) 酶的催化下合成。
T3444	Merimepodib 美泊地布,VX-497,VI-21497	Dehydrogenase; Antiviral; HCV Protease; HBV	Immunology/Inflammation; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Merimepodib (VX-497) 是一种新型非竞争性肌苷一磷酸脱氢酶抑制剂，具有广谱抗病毒活性。
T0467	Sildenafil citrate UK-92480 citrate,西地那非柠檬酸盐,枸橼酸西地那非	Apoptosis; PDE; Autophagy	Apoptosis; Autophagy; Metabolism
	Sildenafil citrate (UK-92480 citrate) 是一种磷酸二酯酶 5 抑制剂，IC50为 5.22 nM。
T0245	RS 61443 RS61443,吗替麦考酚酯,Mycophenolate mofetil,TM-MMF	Dehydrogenase	Metabolism
	RS 61443 (Mycophenolate mofetil) 是一种免疫抑制剂，一种非竞争性、选择性和可逆的肌苷一磷酸脱氢酶 (IMPDH) 抑制剂。
T77570	AP-C2	PKA	Tyrosine Kinase/Adaptors
	AP-C2 是一种有效的小分子鸟苷 3',5'-环单磷酸 (cGMP) 依赖性蛋白激酶 II (cGKII) 抑制剂，对 cGKII 的 pIC50 为 5.2。
T9341	Bemnifosbuvir AT-511	Others; HCV Protease; SARS-CoV	Microbiology/Virology; Others; Proteases/Proteasome
	Bemnifosbuvir (AT-511) 是一种口服活性抑制剂，抑制 HCV 病毒复制，具有全基因型抗病毒活性。它有效抑制 SARS-CoV-2 (COVID-19)感染 (EC90=0.47 μM)。
T6676	Sofosbuvir 索非布韦,GS 7977,PSI-7977	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir (GS 7977) 是一种丙型肝炎病毒聚合酶 NS5B 的尿苷单磷酸类似物抑制剂，用作治疗慢性丙型肝炎的抗病毒剂。

化合物

AICAR monophosphate

Cat.No: T21195

Synonym: Aica ribonucleotide,AICA riboside,Acadesine 5'-monophosphate,Z-nucleotide

Target: Others

2'-Deoxyguanosine 5'-monophosphate disodium

Cat.No: T37636

Synonym: 5′-dGMP disodium

Target: Endogenous Metabolite

Adenosine 5'-monophosphate disodium salt

Cat.No: T65979

Synonym: Adenosine Phosphate Disodium,5‘-AMP-NA2

Target: Nucleoside Antimetabolite/Analog

Gemcitabine monophosphate disodium salt

Cat.No: T21329

Synonym: Gemcitabine monophosphate disodium salt monohydrate,Gemcitabine monophosphate disodium,GemMP

Brivudine monophosphate

Cat.No: T68656

Adefovir monophosphate

Cat.No: T71036

Remdesivir nucleoside monophosphate

Cat.No: T39334

Lyxoflavin 5'-monophosphate

Cat.No: T33099

Ribavirin 5'-monophosphate (lithium salt)

Cat.No: T37877

Uridine-3'-monophosphate (sodium salt)

Cat.No: T37375

2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

Cat.No: T35652

Adenosine 3’-monophosphate (sodium salt hydrate)

Cat.No: T35571

Riboflavin 5'-monophosphate (sodium salt hydrate)

Cat.No: T37789

Uridine-5’-monophosphate (sodium salt hydrate)

Cat.No: T36300

Guanosine-2'(3')-monophosphate disodium salt

Cat.No: T22825

Gemcitabine monophosphate sodium salt hydrate

Cat.No: T4187

Target: Others, DNA, DNA/RNA Synthesis, Autophagy

Leniolisib phosphate

Cat.No: T5166L

Synonym: Leniolisib monophosphate

Inosine-5'-monophosphate (sodium salt hydrate)

Cat.No: T22869

Target: Others

N6-Methyladenosine 5'-monophosphate disodium salt

Cat.No: T12162

Target: Others

Cat.No: T15339

Synonym: Carbidopa 4′-monophosphate

Target: Dopamine Receptor

Acyclovir monophosphate

Cat.No: T60709

Cat.No: T1129

Synonym: Benzoylthiamine monophosphate,S-Benzoylthiamine O-monophosphate,苯磷硫胺

Target: Others

Thymolphthalein monophosphate disodium hydrate

Cat.No: T75377

Cat.No: T39890

Synonym: 8-Bromoadenosine 5'-monophosphate,8-Bromo-AMP,8-Bromoadenylicacid

D-myo-Inositol 4-monophosphate

Cat.No: T77247

Adenosine 5’-monophosphate triethylammonium salt

Cat.No: TNU1647

Inosine-5'-monophosphate Disodium Salt heptahydrate

Cat.No: T67245

1,N6-Ethenoadenosine 5'-monophosphate sodium

Cat.No: T83472

Synonym: 1,N6-ε-AMP sodium,1,N6-Etheno-AMP sodium

2’-O-Methyladenosine 5’-monophosphate triethyl ammonium

Cat.No: TNU1275

2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethylammonium

Cat.No: T75195

2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethylammonium

Cat.No: T75198

2’-O-Methyladenosine 5’-monophosphate triethyl ammonium

Cat.No: T75196

2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium

Cat.No: T75197

2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium

Cat.No: TNU1259

2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium

Cat.No: TNU1276

2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium

Cat.No: T75188

2’-Deoxy-2’-fluoroadenosine 5’-monophosphate triethyl ammonium

Cat.No: TNU1274

Cat.No: T7447

Target: HBV, Reverse Transcriptase, Telomerase

2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium

Cat.No: TNU1277

Fosifloxuridine nafalbenamide

Cat.No: T33762

Synonym: NUC-3373,NUC3373,NUC 3373

Target: DNA/RNA Synthesis

2’-O-Methyl-N6-methyladenosine 5’-monophosphate triethylammonium salt (60091-05-6 neutral molecule)

Cat.No: TNU1630

2'-O-Succinyl-cAMP

Cat.No: T35421

Vidarabine phosphate

Cat.No: T20048

Target: Antiviral

Sulbactum Sodium

Cat.No: T8735

Synonym: 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸

Target: Others

Cat.No: T3444

Synonym: 美泊地布,VX-497,VI-21497

Target: Dehydrogenase, Antiviral, HCV Protease, HBV

Sildenafil citrate

Cat.No: T0467

Synonym: UK-92480 citrate,西地那非柠檬酸盐,枸橼酸西地那非

Target: Apoptosis, PDE, Autophagy

Cat.No: T0245

Synonym: RS61443,吗替麦考酚酯,Mycophenolate mofetil,TM-MMF

Target: Dehydrogenase

Cat.No: T77570

Target: PKA

Cat.No: T9341

Synonym: AT-511

Target: Others, HCV Protease, SARS-CoV

Cat.No: T6676

Synonym: 索非布韦,GS 7977,PSI-7977

Target: HCV Protease

Cat. No.	Product Name	Target	Signaling Pathways
T4925	Thiamine monophosphate chloride (dihydrate) Thiamine monophosphate chloride dihydrat,胺氯化亚磷酸酯,Aneurine monophosphate chloride	Others; Endogenous Metabolite	Metabolism; Others
	Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) 是内源性代谢产物的一种。
T2133	Adenosine monophosphate 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate	Endogenous Metabolite; AMPK	Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
	Adenosine monophosphate (AMP) 是一种嘌呤核糖核苷5'-单磷酸腺苷，是信号转导和调节能量稳态的关键细胞代谢物。它具有EC 3.1.3.11(果糖-二磷酸酶)抑制剂、EC 3.1.3.1(碱性磷酸酶)抑制剂和腺苷A1受体激动剂的作用。
T4730	Thymidine-5'-monophosphate disodium salt 胸苷酸二钠,Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT	Others; Endogenous Metabolite	Metabolism; Others
	Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) 是内源性代谢产物的一种。
T4737	2'-Deoxyadenosine-5'-monophosphate D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyadenosine-5'-monophosphate (D-AMP) 是一种存在于 DNA 中的脱氧核糖核苷酸，是一种核酸 AMP 衍生物。它能够用于研究 DNA 合成和 DNA 损伤过程中基于腺苷的相互作用。
TMA2440	Uridine 5'-monophosphate disodium salt 尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate	Others	Others
	Uridine 5'-monophosphate disodium salt (Disodium UMP) 是合成 RNA 的一种重要成分。
TMO2752	Cytidine 5'-monophosphate 5'-Cytidylic acid,5'-CMP,胞苷酸,Cytidylic Acid	Others; Endogenous Metabolite	Metabolism; Others
	Cytidine 5'-monophosphate (5'-Cytidylic acid) 是一种核苷酸，是组成 RNA 的基本单位之一。它由核碱基胞嘧啶，戊糖核糖和磷酸基团组成。
T0853L	Adenosine 5'-monophosphate monohydrate 5'-AMP,腺苷-5'-单磷酸一水合物,5'-AMP monohydrate,5'-Adenylic acid	AMPK; Adenosine Receptor; HSV	Chromatin/Epigenetic; GPCR/G Protein; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
	Adenosine 5'-monophosphate monohydrate (5'-AMP) 是一种核苷酸，用作 RNA 中的单体。它是一个腺苷 A1受体激动剂，对HSV-1和HSV-2具有显著的抗病毒活性。
T5073	Inosine 5'-monophosphate disodium salt hydrate Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,肌苷5-单磷酸二钠盐水合物,Disodium 5'-inosinate monohydrate	Others; Endogenous Metabolite	Metabolism; Others
	Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt) 或肌苷酸是次黄嘌呤的核糖核苷酸，是嘌呤合成过程中形成的第一个核苷酸。
T4718	Uridine 5'-monophosphate Uridylic acid,尿苷5-单磷酸,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid	Others; Endogenous Metabolite	Metabolism; Others
	Uridine 5'-monophosphate (Uridylic acid) 是一种单磷酸盐形式的尿嘧啶核苷酸，能够由从头途径或体内核苷酸和核酸的降解产物获得，是哺乳动物乳中的主要核苷酸类似物。
T40370	2′-Deoxyadenosine 5′-monophosphate disodium	Endogenous Metabolite	Metabolism
	2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.
T39626	Orotidine 5′-monophosphate Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate
	Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase.
T8186	Xanthosine 5'-monophosphate sodium salt XMP,黄苷-5′-单磷酸钠,L-XMP Sodium	Others	Others
	Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) 是嘌呤代谢的一种中间体。它可用于研究遗传密码，核酸结构以及 DNA，RNA 和蛋白质合成。
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD Monosodium-GMP,cGMP sodium salt,鸟苷-3',5'-环磷酸一钠盐,Cyclic GMP	PKA	Tyrosine Kinase/Adaptors
	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) 也称为 cGMP，是一种细胞调节剂，被描述为第二信使。它的水平随着各种激素的增加而增加，包括乙酰胆碱、胰岛素和催产素。 cGMP 激活蛋白激酶 G(PKG) 并调节离子通道电导，信号传导影响多种过程，包括平滑肌松弛和增殖、光转导和能量稳态。
T4685	INOSINIC ACID Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P	Endogenous Metabolite	Metabolism
	Inosinic acid (IMP) 是内源性代谢产物。
T4731	2'-Deoxycytidine-5'-monophosphoric acid dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) 被用作尿苷单磷酸(UMP)或胞苷单磷酸(CMP)激酶的底物，形成 dCDP，在磷酸化成 dCTP 后支持 DNA 的生物合成。
T20054	Adenosine-2'-monophosphate 2'-Adenylic acid
	2'-Adenylic acid is an agent of bioactive chemical.
T4901	5'-Guanylic acid disodium salt Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5	Others; Endogenous Metabolite	Metabolism; Others
	5'-Guanylic acid disodium salt (GMP-5) 由鸟嘌呤，核糖和磷酸组成，是信使 RNA 中的一种核苷酸单体。鸟苷衍生物参与细胞内信号转导，并已鉴定存在于端粒，核糖体 DNA，免疫球蛋白重链转换区和原癌基因的控制区中的重复基因组序列中。
TCO2745	Cyclic AMP Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate	Others; Endogenous Metabolite	Metabolism; Others
	Cyclic AMP (cAMP)(Adenosine 3',5'-cyclophosphate) 是有丝分裂信使，可以促进 G1期到 S 期的细胞周期进程。
T4735	2'-Deoxyuridine 5'-monophosphate disodium 2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyuridine 5'-monophosphate disodium (2'-dUMP⋅2Na) salt 能够被双底物酶胸苷酸合酶(TS) 还原甲基化为 dTMP (2'-deoxythymidine 5'-monophosphate)。其中 dTMP 是 DNA 合成所需的核苷酸。
T75676	Orotidine 5′-monophosphate trisodium
	Orotidine 5'-monophosphate trisodium 是一种嘧啶核苷酸。Orotidine 5'-monophosphate trisodium 是通过从头合成途径合成的，用于在大量微生物中合成 DNA，包括 M. tuberculosis、S. cerevisiae、S. typhimurium 和 P. falciparum 等等。乳清酸磷酸核糖基转移酶 (OPRT) 以磷酸核糖焦磷酸 (PRPP) 和乳清酸 (OA) 作为底物催化合成 Orotidine 5'-monophosphate trisodium[1]
T2185	L-Ascorbic acid 2-phosphate trisodium L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐	Reactive Oxygen Species; c-Met/HGFR; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB; Tyrosine Kinase/Adaptors
	L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) 是长效的维生素 C 衍生物，能够刺激胶原蛋白的表达和形成。Sodium L-ascorbyl-2-phosphate 提高成骨细胞分化过程中 hASC 中的碱性磷酸酶活性和 runx2A 的表达，因此，能够促进人脂肪干细胞的成骨分化。
T19346	5'-Guanylic acid 鸟苷酸,5'-guanosine monophosphate,5'-GMP	Endogenous Metabolite	Metabolism
	5'-Guanylic acid (5'-guanosine monophosphate) 与几种代谢紊乱有关，包括腺苷脱氨酶缺乏症、 aica-核糖体途径、腺嘌呤磷酸转移酶缺乏症 (aprt) 以及 2-羟基葡糖酸盐途径。
T1335	Mycophenolic acid 霉酚酸,Mycophenolate,RS-61443	Apoptosis; Dehydrogenase; Endogenous Metabolite; Antibacterial; Antibiotic; UGT; Antifungal	Apoptosis; Metabolism; Microbiology/Virology
	Mycophenolic acid (Mycophenolate) 是一种有效的非竞争性肌苷单磷酸脱氢酶 (IMPDH) 抑制剂，EC50为 0.24 µM。它对多种 RNA 病毒具有抗病毒作用。它也是一种免疫抑制剂，具有抗血管生成和抗肿瘤作用。
T40426	Cytidine 5'-diphosphate trisodium salt CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐	Others	Others
	Cytidine 5'-diphosphate trisodium salt (CDP) 可通过尿苷单磷酸激酶 (UMPK) 催化将磷酸基从 ATP 转移到胞苷一磷酸 (CMP) 生成用于合成 DNA 和 RNA 的胞苷三磷酸。
T7327	7-Methoxyisoflavone	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	7-Methoxyisoflavone 是单磷酸腺苷活化蛋白激酶 (AMPK) 的激活剂，是异黄酮衍生物。
T5084	Xanthosine dihydrate 黄苷二水合物	Others; Endogenous Metabolite	Metabolism; Others
	Xanthosine dihydrate 是衍生自黄嘌呤和核糖的核苷，能够提高牛和山羊的乳腺干细胞数量和产奶量。
T6293	Mycophenolate Mofetil TM-MMF,吗替麦考酚酯,RS 61443	Apoptosis; Dehydrogenase; Drug Metabolite	Apoptosis; Metabolism
	Mycophenolate Mofetil (TM-MMF) 是 Mycophenolic acid 的吗啉乙酯前药。它通过抑制肌苷一磷酸脱氢酶抑制从头嘌呤合成，显示出选择性淋巴细胞抗增殖作用。
T4S0792	Pinoresinol 4-O-β-D-glucopyranoside (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside	Others	Others
	(+)-pinoresinol-β-D-glucoside; (+)-pinor 是连翘中主要的活性呋喃类木脂素。它显示出抗氧化、降血压和环磷酸腺苷 (cAMP) 磷酸二酯酶抑制活性。
PDK0014	3-Methylxanthine	Endogenous Metabolite	Metabolism
	3-Methylxanthine 是一种黄嘌呤衍生物和环磷酸鸟苷（GMP）抑制剂，在豚鼠分离的气管肌肉中测得其IC50值为 920 μM。
T5067	Flavin adenine dinucleotide disodium salt Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2	Others; Endogenous Metabolite	Metabolism; Others
	Flavin adenine dinucleotide disodium salt (FAD sodium salt) 是一种辅酶，作用是促进细胞氧化还原反应中黄素酶的电子转移。
T4758	2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine (Deoxyribose cytidine) 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。
TN3013	4,5-Dimethoxycanthin-6-one Methylnigakinone	P450; Antibacterial; PDE	Metabolism; Microbiology/Virology
	4,5-Dimethoxycanthin-6-one 从 Picrasma quassioides BENNET (Simaroubaceae)是一种从 Picrasma quassioides BENNET (Simaroubaceae) 中分离得到生物碱。4,5-Dimethoxycanthin-6-one 是一种有效的、非竞争性的 CYP1A2 介导的 phenacetin O-deethylation 抑制剂（IC50 ： 1.7 μM, Ki ： 2.6 μM），对环磷酸腺苷（cAMP）磷酸二酯酶有很强的抑制作用。4,5-Dimethoxycanthin-6-one 具有抗菌活性，对金黄色葡萄球菌及其耐药菌株有抑制作用。4,5-Dimethoxycanthin-6-one 对肿瘤细胞株 U937 和 HepG2 具有细胞毒性。
TN1841	Kushenol A 苦参新醇 A,Leachianone E	cAMP	GPCR/G Protein
	Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kushenol A and kushenol C exhibit inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).
TN4433	Licoarylcoumarin	cAMP; HIV Protease; Antifection	GPCR/G Protein; Microbiology/Virology; Proteases/Proteasome
	Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effects on xanthine oxidase.
TN5147	Tilifodiolide	IL Receptor; TNF; GABA Receptor	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effects mediated by nitric oxide and cyclic guanosine monophosphate, it also showed anxiolytic and antidepressant effects by the partial involvement of gamma-Aminobutyric acid (GABA) receptors and the possible participation of α2-adrenoreceptors, respectively.
T35770	Cylindrospermopsin
	Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 &#181M, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &...

天然产物

Thiamine monophosphate chloride (dihydrate)

Cat.No: T4925

Synonym: Thiamine monophosphate chloride dihydrat,胺氯化亚磷酸酯,Aneurine monophosphate chloride

Target: Others, Endogenous Metabolite

Adenosine monophosphate

Cat.No: T2133

Synonym: 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate

Target: Endogenous Metabolite, AMPK

Thymidine-5'-monophosphate disodium salt

Cat.No: T4730

Synonym: 胸苷酸二钠,Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT

Target: Others, Endogenous Metabolite

2'-Deoxyadenosine-5'-monophosphate

Cat.No: T4737

Synonym: D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸

Target: Others, Endogenous Metabolite

Uridine 5'-monophosphate disodium salt

Cat.No: TMA2440

Synonym: 尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate

Target: Others

Cytidine 5'-monophosphate

Cat.No: TMO2752

Synonym: 5'-Cytidylic acid,5'-CMP,胞苷酸,Cytidylic Acid

Target: Others, Endogenous Metabolite

Adenosine 5'-monophosphate monohydrate

Cat.No: T0853L

Synonym: 5'-AMP,腺苷-5'-单磷酸一水合物,5'-AMP monohydrate,5'-Adenylic acid

Target: AMPK, Adenosine Receptor, HSV

Inosine 5'-monophosphate disodium salt hydrate

Cat.No: T5073

Synonym: Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,肌苷5-单磷酸二钠盐水合物,Disodium 5'-inosinate monohydrate

Target: Others, Endogenous Metabolite

Uridine 5'-monophosphate

Cat.No: T4718

Synonym: Uridylic acid,尿苷5-单磷酸,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid

Target: Others, Endogenous Metabolite

2′-Deoxyadenosine 5′-monophosphate disodium

Cat.No: T40370

Target: Endogenous Metabolite

Orotidine 5′-monophosphate

Cat.No: T39626

Synonym: Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate

Xanthosine 5'-monophosphate sodium salt

Cat.No: T8186

Synonym: XMP,黄苷-5′-单磷酸钠,L-XMP Sodium

Target: Others

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD

Cat.No: T5065

Synonym: Monosodium-GMP,cGMP sodium salt,鸟苷-3',5'-环磷酸一钠盐,Cyclic GMP

Target: PKA

Cat.No: T4685

Synonym: Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P

Target: Endogenous Metabolite

2'-Deoxycytidine-5'-monophosphoric acid

Cat.No: T4731

Synonym: dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate

Target: Others, Endogenous Metabolite

Adenosine-2'-monophosphate

Cat.No: T20054

Synonym: 2'-Adenylic acid

5'-Guanylic acid disodium salt

Cat.No: T4901

Synonym: Guanosine 5'-monophosphate disodium salt,5'-鸟苷酸二钠,鸟苷钠5'-单磷酸,GMP-5

Target: Others, Endogenous Metabolite

Cat.No: TCO2745

Synonym: Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate

Target: Others, Endogenous Metabolite

2'-Deoxyuridine 5'-monophosphate disodium

Cat.No: T4735

Synonym: 2'-脱氧尿苷-5'-单磷酸二钠,2'-dUMP⋅2Na,2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐,2'-Deoxyuridine 5'-monophosphate disodium salt

Target: Others, Endogenous Metabolite

Orotidine 5′-monophosphate trisodium

Cat.No: T75676

L-Ascorbic acid 2-phosphate trisodium

Cat.No: T2185

Synonym: L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐

Target: Reactive Oxygen Species, c-Met/HGFR, Endogenous Metabolite

5'-Guanylic acid

Cat.No: T19346

Synonym: 鸟苷酸,5'-guanosine monophosphate,5'-GMP

Target: Endogenous Metabolite

Mycophenolic acid

Cat.No: T1335

Synonym: 霉酚酸,Mycophenolate,RS-61443

Target: Apoptosis, Dehydrogenase, Endogenous Metabolite, Antibacterial, Antibiotic, UGT, Antifungal

Cytidine 5'-diphosphate trisodium salt

Cat.No: T40426

Synonym: CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐

Target: Others

7-Methoxyisoflavone

Cat.No: T7327

Target: AMPK

Xanthosine dihydrate

Cat.No: T5084

Synonym: 黄苷二水合物

Target: Others, Endogenous Metabolite

Mycophenolate Mofetil

Cat.No: T6293

Synonym: TM-MMF,吗替麦考酚酯,RS 61443

Target: Apoptosis, Dehydrogenase, Drug Metabolite

Pinoresinol 4-O-β-D-glucopyranoside

Cat.No: T4S0792

Synonym: (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside

Target: Others

3-Methylxanthine

Cat.No: PDK0014

Target: Endogenous Metabolite

Flavin adenine dinucleotide disodium salt

Cat.No: T5067

Synonym: Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2

Target: Others, Endogenous Metabolite

2'-Deoxycytidine

Cat.No: T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物

Target: Endogenous Metabolite

4,5-Dimethoxycanthin-6-one

Cat.No: TN3013

Synonym: Methylnigakinone

Target: P450, Antibacterial, PDE

Cat.No: TN1841

Synonym: 苦参新醇 A,Leachianone E

Target: cAMP

Licoarylcoumarin

Cat.No: TN4433

Target: cAMP, HIV Protease, Antifection

Cat.No: TN5147

Target: IL Receptor, TNF, GABA Receptor

Cylindrospermopsin

Cat.No: T35770

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