|
TMPY-04935
|
CD47 Protein, Human, Recombinant (aa 1-139, His)
MER6,CD47 molecule,IAP,OA3
|
Human
|
HEK293
|
|
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b... |
|
TMPY-03763
|
Neuropilin-2 Protein, Human, Recombinant (hFc)
Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2
|
Human
|
HEK293
|
|
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation factor V/VIII homology domains, and a MAM (meprin, tyrosine phosphatase domain) region. NRP-2 is a receptor capable of binding two disparate ligands, classⅢ semaphorins (SEMA) and vascular endothelial growth factors (VEGF), and thus regulates two diverse systems by activating cellul... |
|
TMPY-00132
|
Mesothelin Protein, Human, Recombinant
MPF,SMRP,Mesothelin
|
Human
|
HEK293
|
|
The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamo... |
|
TMPY-06986
|
FGF-8b Protein, Human, Recombinant
NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...
|
Human
|
E. coli
|
|
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... |
|
TMPY-05191
|
CD47 Protein, Human, Recombinant, Biotinylated
CD47 molecule,MER6,OA3,IAP
|
Human
|
HEK293
|
|
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b... |
|
TMPY-04683
|
CD47 Protein, Human, Recombinant
MER6,CD47 molecule,OA3,IAP
|
Human
|
HEK293
|
|
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b... |
|
TMPY-00072
|
GITR/TNFRSF18 Protein, Human, Recombinant (His)
AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...
|
Human
|
HEK293
|
|
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... |
|
TMPY-00892
|
Neuropilin-2 Protein, Human, Recombinant (His)
NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2
|
Human
|
HEK293
|
|
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation factor V/VIII homology domains, and a MAM (meprin, tyrosine phosphatase domain) region. NRP-2 is a receptor capable of binding two disparate ligands, classⅢ semaphorins (SEMA) and vascular endothelial growth factors (VEGF), and thus regulates two diverse systems by activating cellul... |
|
TMPY-01020
|
Periostin/OSF-2 Protein, Human, Recombinant (His)
PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto...
|
Human
|
HEK293
|
|
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced ... |
|
TMPY-01897
|
PRSS3 Protein, Human, Recombinant (His)
PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M...
|
Human
|
HEK293
|
|
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ... |
|
TMPY-01180
|
CD86 Protein, Human, Recombinant (His)
CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72
|
Human
|
HEK293
|
|
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B ... |
|
TMPY-05748
|
CD45 Protein, Human, Recombinant (aa 26-577, His)
L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty...
|
Human
|
HEK293
|
|
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... |
|
TMPY-04142
|
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re...
|
Human
|
HEK293
|
|
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. It is an essential mediator for osteoclast and lymph node development. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It can interact with various TRAF family proteins, through which this recep... |
|
TMPJ-01099
|
IL-15RA Protein, Human, Recombinant (hFc)（Human Cells）
interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...
|
Human
|
Human Cells
|
|
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun... |
|
TMPY-04298
|
CDCP1 Protein, Human, Recombinant (His)
TRASK,CD318,CUB domain containing protein 1,SIMA1
|
Human
|
HEK293
|
|
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migratio... |
|
TMPY-00480
|
NCAM1 Protein, Human, Recombinant (His)
neural cell adhesion molecule 1,CD56,MSK39,NCAM
|
Human
|
HEK293
|
|
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. NCAM1 is involved in neuron-neuron adhesion, neurite fasciculation, the outgrowth of neurites, etc. It has also been shown to be... |
|
TMPY-00357
|
HNT/NTM Protein, Human, Recombinant (His)
HNT,NTRI,IGLON2,neurotrimin
|
Human
|
HEK293
|
|
NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. IgLONs have been associated with psychiatric disorders, intelligence, body weight, heart disease, and tumors. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. Neurotrimin is a mem... |
|
TMPY-03149
|
CDCP1 Protein, Human, Recombinant (mFc)
TRASK,SIMA135,CD318,CUB domain containing ...
|
Human
|
HEK293
|
|
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migratio... |
|
TMPK-00447
|
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3....
|
Human
|
HEK293
|
|
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. |
|
TMPY-03621
|
EphB2 Protein, Mouse, Recombinant (hFc)
Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,Prkm5,Sek<...
|
Mouse
|
HEK293
|
|
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. EphB2 receptor tyrosine kinase phosphorylates syndecan-2 and that this phosphorylation event is crucial for syndecan-2 clustering and spine formation. The Eph family of receptor tyrosine kinases (comp... |
|
TMPY-01268
|
SMYD3 Protein, Human, Recombinant (GST)
SET and MYND domain containing 3,ZMYND1,KMT3
|
Human
|
Baculovirus-Insect Cells
|
|
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg... |
|
TMPY-04386
|
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,...
|
Human
|
Baculovirus-Insect Cells
|
|
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. EphB2 receptor tyrosine kinase phosphorylates syndecan-2 and that this phosphorylation event is crucial for syndecan-2 clustering and spine formation. The Eph family of receptor tyrosine kinases (comp... |
|
TMPJ-01288
|
KLF6 Protein, Human, Recombinant
CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...
|
Human
|
E. coli
|
|
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul... |
|
TMPY-03960
|
COL9A1 Protein, Human, Recombinant (His)
EDM6,collagen, type IX, α1,STL4,collagen, type IX, alpha 1,M...
|
Human
|
HEK293
|
|
|
|
TMPY-04015
|
COL9A1 Protein, Human, Recombinant (mFc)
DJ149L1.1.2,STL4,collagen, type IX, alpha 1,MED,EDM6,collage...
|
Human
|
HEK293
|
|
|
|
TMPY-05514
|
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor superfamil...
|
Human
|
HEK293
|
|
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. It is an essential mediator for osteoclast and lymph node development. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It can interact with various TRAF family proteins, through which this recep... |
|
TMPK-00398
|
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Fibroblast growth factor receptor 2,CD332,...
|
Human
|
HEK293
|
|
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors... |
|
TMPK-00401
|
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD...
|
Human
|
HEK293
|
|
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. |
|
TMPJ-00391
|
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR2,FGFR2 beta,CD3
|
Human
|
Human Cells
|
|
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. A frequent splici... |
|
TMPY-00276
|
PLGF/PGF Protein, Human, Recombinant (mFc)
placental growth factor,D12S1900,PLGF,SHGC-10760,PGFL,PlGF-2
|
Human
|
HEK293
|
|
|
|
TMPY-06411
|
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
CD357,GITR-D,tumor necrosis factor receptor superfa...
|
Human
|
HEK293
|
|
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... |
|
TMPY-03883
|
CD47 Protein, Human, Recombinant (hFc)
OA3,CD47 molecule,IAP,MER6
|
Human
|
HEK293
|
|
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b... |
|
TMPY-02573
|
IL-17RC Protein, Human, Recombinant (aa 1-454, His)
IL17RL,interleukin 17 receptor C,IL17-RL,UNQ6118/PRO20040/PR...
|
Human
|
Baculovirus-Insect Cells
|
|
IL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the prostate, skin, and other tissues. The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies before clinical applicati... |
|
TMPY-03969
|
SUSD4 Protein, Human, Recombinant (mFc)
sushi domain containing 4,PRO222
|
Human
|
HEK293
|
|
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical path... |
|
TMPJ-00465
|
PTP1C Protein, Human, Recombinant (His)
HCP,Hematopoietic Cell Protein-Tyrosine Phosphatase,SH-PTP1,...
|
Human
|
E. coli
|
|
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter... |
|
TMPY-00715
|
CD84 Protein, Human, Recombinant (His)
LY9B,mCD84,CD84 molecule,hCD84,SLAMF5
|
Human
|
HEK293
|
|
The CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunore... |
|
TMPY-01656
|
VEGF183 Protein, Human, Recombinant
血管内皮生长因子,VEGF165,VPF,VEGF,vascular endothelial growth factor...
|
Human
|
Baculovirus-Insect Cells
|
|
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... |
|
TMPY-04216
|
EphB2 Protein, Mouse, Recombinant (His)
Drt,Nuk,Qek5,Tyro5,Prkm5,Sek3,ETECK,Cek5,Hek5,EPH r...
|
Mouse
|
HEK293
|
|
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. EphB2 receptor tyrosine kinase phosphorylates syndecan-2 and that this phosphorylation event is crucial for syndecan-2 clustering and spine formation. The Eph family of receptor tyrosine kinases (comp... |
|
TMPK-00400
|
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Fibroblast growth factor receptor 2,KGFR,FGFR-2,KSAM,CD3...
|
Human
|
HEK293
|
|
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors... |
|
TMPY-05590
|
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated
NCAM,MSK39,CD56,neural cell adhesion molecule 1
|
Human
|
HEK293
|
|
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. NCAM1 is involved in neuron-neuron adhesion, neurite fasciculation, the outgrowth of neurites, etc. It has also been shown to be... |
|
TMPY-04157
|
RANK/TNFRSF11A Protein, Human, Recombinant (His)
ODFR,OFE,CD265,PDB2,RANK,tumor necrosis factor receptor supe...
|
Human
|
HEK293
|
|
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. It is an essential mediator for osteoclast and lymph node development. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It can interact with various TRAF family proteins, through which this recep... |
|
TMPK-00399
|
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
Keratinocyte growth factor receptor,K-sam,BEK,FGFR2 β (IIIb)...
|
Human
|
HEK293
|
|
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors... |
|
TMPY-01692
|
NETO1 Protein, Human, Recombinant (His)
neuropilin (NRP) and tolloid (TLL)-like 1,BCTL1,BTCL1
|
Human
|
HEK293
|
|
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus repr... |
|
TMPY-03705
|
VEGF164 Protein, Canine, Recombinant
血管内皮生长因子,vascular endothelial growth factor A
|
Canine
|
HEK293
|
|
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular per... |
|
TMPJ-00390
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FGFR2IIIb Protein, Human, Recombinant (hFc)
FGFR2,FGFR2 beta,FGFR2 β,FGFR2IIIb,KGFR,FGF R2b,BFR-1,FGFR2b...
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Human
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Human Cells
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FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. A frequent splici... |
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TMPK-00729
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Siglec-6 Protein, Human, Recombinant (His & Avi)
SIGLEC6,OBBP1,CD327,CD33L1,CD...
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Human
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HEK293
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Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains.Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
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TMPY-05246
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CD86 Protein, Human, Recombinant (His), Biotinylated
CD28LG2,B70,B7.2,LAB72,CD86 antigen,B7-2
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Human
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HEK293
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CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B ... |
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TMPY-05233
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GITR/TNFRSF18 Protein, Human, Recombinant (His), Biotinylated
GITR-D,CD357,AITR,GITR,tumor necrosis factor recept...
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Human
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HEK293
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GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... |
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TMPY-04408
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CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)
calcium/calmodulin-dependent protein kinase II beta,CAM2,CAM...
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Human
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Baculovirus-Insect Cells
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Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in prostate cancer cells ability to escape apoptosis under androgen ablation and facilitate the progression of prostate cancer cells to an androgen independent state. As a multifunctional protein kinase, the loss of activity may play a critical role in initiating the changes leading to... |
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TMPY-02691
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IL-17RC Protein, Human, Recombinant(aa 1-454, hFc)
IL17RL,interleukin 17 receptor C,UNQ6118/PRO20040/PRO3
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Human
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HEK293
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IL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the prostate, skin, and other tissues. The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies before clinical applicati... |
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