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Search Results for " aa-115 "

Targets Recommended: Mdm2

1

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T14303	Alrizomadlin APG-115,AA-115	Mdm2	Apoptosis
	Alrizomadlin (APG-115) 是一种具有口服活性的 MDM2 抑制剂，IC50 为 3.8 nM，Ki 分别为 1 nM[1]。 Alrizomadlin 阻断 MDM2 和 p53 的相互作用，并以 p53 依赖性方式诱导细胞周期停滞和细胞凋亡。

化合物

Cat.No: T14303

Synonym: APG-115,AA-115

Target: Mdm2

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01907	VSIG4 Protein, Human, Recombinant (His) Z39IG,CRIg,V-set and immunoglobulin domain containing 4	Human	HEK293
	VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that a...
TMPJ-01359	Siglec-8 Protein, Human, Recombinant (hFc) SAF2,CD329 antigen,CDw329,Siglec-8,SAF2SAF-2,SAF-2,Siglec8	Human	Human Cells
	Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Siglec-8 is expressed on eosinophils, basophils, and mast cells, and it shows a binding preference for the carbohydrate 6-O sulfated sLex. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Mature human Siglec-8 c...
TMPJ-01361	Siglec-8 Protein, Human, Recombinant (mFc) CD329 antigen,Siglec-8,SAF2SAF-2,CDw329,Siglec8,SAF-2,SAF2	Human	Human Cells
	Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Siglec-8 is expressed on eosinophils, basophils, and mast cells, and it shows a binding preference for the carbohydrate 6-O sulfated sLex. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Mature human Siglec-8 c...
TMPJ-01360	Siglec-8 Protein, Human, Recombinant (His) Siglec8,SAF-2,SAF2SAF-2,Siglec-8,SAF2,CD329 antigen,CDw329	Human	Human Cells
	Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Siglec-8 is expressed on eosinophils, basophils, and mast cells, and it shows a binding preference for the carbohydrate 6-O sulfated sLex. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Mature human Siglec-8 c...
TMPY-01309	VSIG4 Protein, Mouse, Recombinant (His) Z39IG,V-set and immunoglobulin domain containing 4,CRIg,BC02...	Mouse	HEK293
	VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that a...
TMPY-03528	VSIG4 Protein, Human, Recombinant (hFc) CRIg,Z39IG,V-set and immunoglobulin domain containing 4	Human	HEK293
	VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that a...
TMPY-05370	VSIG4 Protein, Human, Recombinant (hFc), Biotinylated CRIg,Z39IG,V-set and immunoglobulin domain containing 4	Human	HEK293
	VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that a...
TMPY-01091	VSIG4 Protein, Mouse, Recombinant (His & hFc) CRIg,Z39IG,A530061A11,BC025105,V-set and immunoglobulin doma...	Mouse	HEK293
	VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that a...

重组蛋白

VSIG4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01907

Species: Human

Expression System: HEK293

Siglec-8 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01359

Species: Human

Expression System: Human Cells

Siglec-8 Protein, Human, Recombinant (mFc)

Cat.No: TMPJ-01361

Species: Human

Expression System: Human Cells

Siglec-8 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01360

Species: Human

Expression System: Human Cells

VSIG4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01309

Species: Mouse

Expression System: HEK293

VSIG4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03528

Species: Human

Expression System: HEK293

VSIG4 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05370

Species: Human

Expression System: HEK293

VSIG4 Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01091

Species: Mouse

Expression System: HEK293

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