SNIPER

Cat. No.	Product Name	CAS No.	Purity
T13837	PROTAC CRABP-II Degrader-2 化合物 T13837	1225383-38-9	98%
T13837	PROTAC CRABP-II Degrader-2 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1.
T18687	SNIPER(ABL)-020 化合物 T18687	T18687	98%
T18687	SNIPER(ABL)-020 is a chemical compound consisting of Dasatinib, an ABL inhibitor, and Bestatin, an IAP ligand, conjugated with a linker. This compound effectivel...
T16905	SNIPER(BRD)-1 化合物 T16905	2095244-54-3	98%
T16905	SNIPER(BRD)-1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+)-JQ-1, linked together. It promotes the degr...
T13836	PROTAC CRABP-II Degrader-1 化合物 T13836	1225383-40-3	98%
T13836	PROTAC CRABP-II Degrader-1 is a potent degrader of cellular retinoic acid binding protein (CRABP-II) based on cIAp1.
T18686	SNIPER(ABL)-019 化合物 T18686	T18686	98%
T18686	SNIPER(ABL)-019, conjugating Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM[1].
T13892	SNIPER(TACC3)-2 化合物 T13892	T13892	98%
T13892	SNIPER(TACC3)-2 targets TACC3 protein degradation via the ubiquitin-proteasome pathway. It induces cancer cell death.
T18692	SNIPER(ABL)-047 化合物 T18692	T18692	98%
T18692	SNIPER(ABL)-047, conjugating HG-7-85-01 (ABL inhibitor) to MV-1 (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 2 μM[1].
T18694	SNIPER(ABL)-050 化合物 T18694	T18694	98%
T18694	SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker. This conjugation results in the reduct...
T17545	Biotin-BS 化合物 T17545	T17545	98%
T17545	Biotin-BS is a chemical compound composed of two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and biotin. These ligands are interconnected through linkers....
T18688	SNIPER(ABL)-024 化合物 T18688	2222355-77-1	98%
T18688	SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5μM[1]...
T18605	PROTAC ERα Degrader-2 化合物 T18605	1351169-29-3	98%
T18605	PROTAC ERα Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. ...
T18690	SNIPER(ABL)-039 化合物 T18690	2222354-29-0	98%
T18690	SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 1...
T18691	SNIPER(ABL)-044 化合物 T18691	T18691	98%
T18691	SNIPER(ABL)-044, conjugating HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM[1]....
T18697	SNIPER(ER)-87 化合物 T18697	2222354-91-6	98%
T18697	SNIPER(ER)-87 is a chemical compound composed of a derivative of the inhibitor of apoptosis protein (IAP) ligand LCL161 conjugated to the estrogen receptor α (ER...
T18684	SNIPER(ABL)-013 化合物 T18684	T18684	98%
T18684	SNIPER(ABL)-013, conjugating GNF5 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 20 μM[1].
T17706	BzNH-BS 化合物 T17706	T17706	98%
T17706	BzNH-BS is a chemical compound comprising two distinct ligands: methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide. The ligands are interconnected through linker...
T18695	SNIPER(ABL)-058 化合物 T18695	2222354-61-0	98%
T18695	SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10...
T18635	PROTAC RAR Degrader-1 化合物 T18635	1351169-27-1	98%
T18635	PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degr...
T18693	SNIPER(ABL)-049 化合物 T18693	T18693	98%
T18693	SNIPER(ABL)-049, conjugating Imatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 100 μM[1].
T18596	PROTAC AR Degrader-4 化合物 T18596	1351169-31-7	98%
T18596	PROTAC AR Degrader-4 comprises a cIAP1 ligand binding group, a linker and an androgen receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degrad...