Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Diethyl-pythiDC 是一种胶原蛋白脯氨酰 4-羟化酶抑制剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 357 | 现货 | ||
5 mg | ¥ 897 | 现货 | ||
10 mg | ¥ 1,480 | 现货 | ||
25 mg | ¥ 3,130 | 现货 | ||
50 mg | ¥ 4,580 | 现货 | ||
100 mg | ¥ 6,560 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 983 | 现货 |
产品描述 | Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor. |
体外活性 | In MDA-MB-231 cells, Diethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. None of the esterified Diethyl-pythiDC exhibited cytotoxic activity at high micromolar concentrations. Cells treated with dihydroxybenzoate demonstrate a strong iron-deficient phenotype. In contrast, cells treated with Diethyl-pythiDC appear to be normal at concentrations as high as 500 µM. Treatment with Diethyl-pythiDC and low levels of diethyl pyimDC does not affect the level of TfR, HIF-1α, or ferritin[1]. |
分子量 | 306.34 |
分子式 | C14H14N2O4S |
CAS No. | 1821370-70-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 33 mg/mL (107.72 mM), Sonification is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.2643 mL | 16.3217 mL | 32.6435 mL | 81.6087 mL |
5 mM | 0.6529 mL | 3.2643 mL | 6.5287 mL | 16.3217 mL | |
10 mM | 0.3264 mL | 1.6322 mL | 3.2643 mL | 8.1609 mL | |
20 mM | 0.1632 mL | 0.8161 mL | 1.6322 mL | 4.0804 mL | |
50 mM | 0.0653 mL | 0.3264 mL | 0.6529 mL | 1.6322 mL | |
100 mM | 0.0326 mL | 0.1632 mL | 0.3264 mL | 0.8161 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Diethyl-pythiDC 1821370-70-0 Metabolism Others Hydroxylase inhibit Diethyl pythiDC Inhibitor DiethylpythiDC inhibitor