MEK inhibitor kit 包含丝裂原活化/细胞外信号调节激酶 MEK 抑制剂,MEK 可磷酸化靶蛋白上 Ser/Thr 和Tyr 残基,是RAS/RAF-MEK-ERK 信号转导通路的主要组分。MEK 信号通路参与了细胞周期进行、细胞凋亡、迁移、分化、代谢和增殖等过程的调节,MEK 表达水平及其结构的改变与癌症等多种疾病的发生密切相关。TargetMol 为您提供34种精选MEK 抑制剂。所有化合物现货供应,到货快捷,是您预实验探索的不二选择。
ID | Compound | CAS | MW | Concentration | Target |
---|---|---|---|---|---|
T0468 | Lidocaine | 137-58-6 | 234.34 | 10mM | Apoptosis; ERK; Histamine Receptor; MEK; NF-κB; Sodium Channel |
T1144 | Lidocaine hydrochloride | 73-78-9 | 270.8 | 10mM | Apoptosis; ERK; MEK; NF-κB; Sodium Channel |
T2125 | Trametinib | 871700-17-3 | 615.39 | 10mM | Apoptosis; Autophagy; MEK |
T2327 | Pelitinib | 257933-82-7 | 467.92 | 10mM | EGFR; MEK; Raf; Src |
T2378 | RGB-286638 free base | 784210-88-4 | 545.63 | 10mM | CDK; GSK-3; JAK; MEK |
T2416 | BIX02189 | 1094614-85-3 | 440.54 | 10mM | ERK; MEK; TGF-beta/Smad |
T2443 | CI-1040 | 212631-79-3 | 478.67 | 10mM | Apoptosis; MEK |
T2508 | Binimetinib | 606143-89-9 | 441.23 | 10mM | Autophagy; MEK |
T2623 | PD98059 | 167869-21-8 | 267.28 | 10mM | Aryl Hydrocarbon Receptor; Autophagy; ERK; MEK |
T2708 | SL327 | 305350-87-2 | 335.35 | 10mM | DNA/RNA Synthesis; MEK |
T2836 | Isorhamnetin | 480-19-3 | 316.27 | 10mM | Endogenous Metabolite; MEK; PI3K |
T3623 | Cobimetinib | 934660-93-2 | 531.32 | 10mM | Apoptosis; MEK |
T6083 | AZD8330 | 869357-68-6 | 461.23 | 10mM | ERK; MEK |
T6131 | Pimasertib | 1236699-92-5 | 431.2 | 10mM | MEK |
T6152 | PD318088 | 391210-00-7 | 561.09 | 10mM | MEK |
T6189 | Mirdametinib | 391210-10-9 | 482.19 | 10mM | Apoptosis; Autophagy; MEK |
T6218 | Selumetinib | 606143-52-6 | 457.68 | 10mM | Apoptosis; ERK; MEK |
T6324 | BIX02188 | 1094614-84-2 | 412.48 | 10mM | ERK; MEK; TGF-beta/Smad |
T6419 | BMS-536924 | 468740-43-4 | 479.96 | 10mM | Apoptosis; FAK; IGF-1R; MEK; Src |
T6692 | TAK-733 | 1035555-63-5 | 504.23 | 10mM | MEK |
T6760 | APS-2-79 hydrochloride | 2002381-31-7 | 423.89 | 10mM | MAPK; MEK |
T6785 | BI-847325 | 1207293-36-4 | 464.56 | 10mM | Apoptosis; Aurora Kinase; MEK |
T6971 | Ro 5126766 | 946128-88-7 | 471.46 | 10mM | MEK; Raf |
T5S2361 | Epiberberine | 6873-09-2 | 336.36 | 10mM | AChE; AChR; BACE; Beta-secretase; ERK; MEK |
TMS2181 | trans-Zeatin | 1637-39-4 | 219.24 | 10mM | Endogenous Metabolite; ERK; MEK |
T5412 | RO4987655 | 874101-00-5 | 565.28 | 10mM | MEK |
T5857 | Trametinib (DMSO solvate) | 1187431-43-1 | 693.53 | 10mM | Apoptosis; MEK |
T7742 | GW 284543 hydrochloride | 179246-08-3 | 408.87 | 10mM | MEK |
T21295 | BIX02189 | 1265916-41-3 | 440.54 | 10mM | ERK; MEK |
T9321 | zapnometinib | 303175-44-2 | 409.55 | 10mM | Antibacterial; Influenza Virus; MEK |
T21635 | PD184161 | 212631-67-9 | 557.56 | 10mM | MEK |
T27242 | EF24 | 342808-40-6 | 311.33 | 10mM | Caspase; ERK; MEK |
T36631 | BAY-6035 | 2247890-13-5 | 396.48 | 10mM | Histone Methyltransferase;MEK |
T21980 | PD 198306 | 212631-61-3 | 476.23 | 10mM | MEK |
Empty | 1000025-07-9 | 1000413-72-8 | 229005-80-5 | 1000787-75-6 | 946387-07-1 | 1000998-59-3 | 1175526-27-8 | 1001288-58-9 | 1001350-96-4 | 1001404-83-6 | Empty |
Vadadustat | TAK875 | TAK-779 | Tegobuvir | RN-1734 | BMS-687453 | AM211 | FT011 | BMS754807 | AAI101 | ||
Empty | 1001625-82-6 | 1001645-58-4 | 1001753-24-7 | 1001908-89-9 | 1002304-34-8 | 1002-84-2 | 100291-86-9 | 100299-08-9 | 10030-52-1 | 10040-45-6 | Empty |
RPW-24 | SRT1720 hydrochloride | INH6 | SRT 2183 | AMG208 | Pentadecanoic acid | Apiopaeonoside | Pemirolast potassium | L-Anserine nitrate salt | Sodium Picosulfate | ||
Empty | 100427-26-7 | 1004316-88-4 | 10045-45-1 | 100462-37-1 | 1004990-28-6 | 100-51-6 | 1005-24-9 | 1005264-47-0 | 1005334-57-5 | 1005342-46-0 | Empty |
Lercanidipine | Cobicistat | 1-Ethyl-2-benzimidazolinone | ROSIRIDIN | PF-AKT400 | Benzyl alcohol | 1-Methylnicotinamide chloride | MX69 | CVT-10216 | LCL161 | ||
Empty | 1005491-05-3 | 100-55-0 | 1005504-62-0 | 1005883-72-6 | 100643-71-8 | 1007207-67-1 | 10075-50-0 | 1007647-73-5 | 100784-20-1 | 10083-24-6 | Empty |
Tirasemtiv | Roniacol | Rg3039 | Z433927330 | Desloratadine | CH5132799 | 5-Bromoindole | Smurf1-IN-A01 | Halosulfuron-methyl | Piceatannol | ||
Empty | 100872-83-1 | 100874-08-6 | 1009119-64-5 | 1009119-65-6 | 100929-71-3 | 1009298-09-2 | 1009298-59-2 | 100929-99-5 | 1009734-33-1 | 10097-84-4 | Empty |
ML346 | SB 4 | Daclatasvir | Daclatasvir dihydrochloride | NADPH (tetracyclohexanamine) | AZD8055 | Vistusertib | PAβN dihydrochloride | HZ1157 | Rotundine | ||
Empty | 1009816-48-1 | 1009817-63-3 | 1009820-21-6 | 100986-85-4 | 101001-34-7 | 1010411-21-8 | 1010-60-2 | 1011244-68-0 | 1011301-27-1 | 1011529-10-4 | Empty |
Thiamet G | B-AP15 | Silmitasertib | Levofloxacin | Pamicogrel | GSK369796 Dihydrochloride | 2-Chloronaphthoquinone | TFAP | Tenovin3 | Azvudine | ||
Empty | 101152-94-7 | 101155-02-6 | 1011557-82-6 | 1011-74-1 | 101-20-2 | 1012054-59-9 | 101-21-3 | 101-26-8 | 101303-98-4 | 1013101-36-4 | Empty |
Milnacipran hydrochloride | BW-A78U | Tenovin-6 | DL-Normetanephrine hydrochloride | Triclocarban | CUDC101 | Chlorpropham | Mestinon | Zacopride hydrochloride | PF04691502 | ||
Empty | 101-31-5 | 1013-69-0 | 1013750-77-0 | 1013753-99-5 | 10138-52-0 | 1013920-15-4 | 1013937-63-7 | 1014691-61-2 | 101477-54-7 | 101494-95-5 | Empty |
L-Hyoscyamine | Noreugenin | ML-030 | BC-1382 | Gadolinium chloride | Vorolanib | VTP-27999 TFA | GSK0660 | Lomerizine hydrochloride | 8-CHLOROQUINAZOLIN-4(1H)-ONE |