c-Kit inhibitor kit

产品编号 CL0075 c-Kit inhibitor kit

库化合物信息 Excel SDF

c-Kit inhibitor kit 包含 c-Kit 抑制剂，c-Kit 是一种原癌基因，编码Ⅲ型跨膜受体 Tyr 激酶，通过 Ras-Erk，PI3K-AKT 和 JAK- STAT 三条途径来增加细胞内的信号传导，影响细胞的增殖和存活。多种人类癌症是由 c-Kit 激酶结构域突变引起的，这些突变会破坏 c-Kit 的自抑制机制，导致细胞内的信号通路持续激活，促进肿瘤细胞的发生发展。TargetMol 为您提供40种精选c-Kit 抑制剂。所有化合物现货供应，到货快捷，是您预实验探索的不二选择。

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

规格
10 μL * 10 mM (in DMSO)

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产品组成

ID	Compound	CAS	MW	Concentration	Target
T0093L	Sorafenib	284461-73-0	464.83	10mM	Apoptosis; Autophagy; c-Kit; Ferroptosis; FLT; PDGFR; Raf; VEGFR
T0097L	Pazopanib	444731-52-6	437.52	10mM	Autophagy; c-Kit; FGFR; PDGFR; VEGFR
T0374L	Sunitinib	557795-19-4	398.47	10mM	Apoptosis; Autophagy; c-Kit; FLT; IRE1; Mitophagy; PDGFR; VEGFR
T1448L	Dasatinib monohydrate	863127-77-9	506.03	10mM	Apoptosis; Autophagy; Bcr-Abl; c-Kit; Ephrin Receptor; Src
T1452	Axitinib	319460-85-0	386.47	10mM	c-Kit; PDGFR; VEGFR
T1667	Tandutinib	387867-13-2	562.7	10mM	Apoptosis; c-Kit; CSF-1R; FLT; PDGFR; Src
T1792	Regorafenib	755037-03-7	482.82	10mM	Autophagy; c-Kit; c-RET; PDGFR; Raf; VEGFR
T1836	AZD2932	883986-34-3	447.49	10mM	c-Kit; FLT; PDGFR; VEGFR
T2070	Agerafenib	1188910-76-0	517.46	10mM	Bcr-Abl; c-Kit; c-RET; PDGFR; Raf; Src
T2115	Pexidartinib	1029044-16-3	417.81	10mM	Apoptosis; c-Fms; c-Kit; CSF-1R; FLT
T2288	Motesanib	453562-69-1	373.46	10mM	c-Kit; VEGFR
T2500	Cediranib	288383-20-0	450.51	10mM	Autophagy; c-Kit; FLT; PDGFR; VEGFR
T2516	Amuvatinib	850879-09-3	447.51	10mM	Apoptosis; c-Kit; c-Met/HGFR; c-RET; DNA/RNA Synthesis; FLT; PDGFR
T2609	Masitinib	790299-79-5	498.64	10mM	Apoptosis; Bcr-Abl; c-Fms; c-Kit; FAK; FGFR; Hck; PDGFR; Src
T2624	OSI-930	728033-96-3	443.44	10mM	Apoptosis; c-Fms; c-Kit; CSF-1R; FLT; Raf; Src; VEGFR
T3452	ISCK03	945526-43-2	355.46	10mM	c-Kit
T4315	Ki20227	623142-96-1	480.54	10mM	c-Fms; c-Kit; CSF-1R; PDGFR; VEGFR
T4332	c-Kit-IN-1	1225278-16-9	489.47	10mM	c-Kit; c-Met/HGFR
T4349	Sitravatinib	1123837-84-2	629.68	10mM	c-Kit; Discoidin Domain Receptor (DDR); Ephrin Receptor; FLT; TAM Receptor; Trk receptor; VEGFR
T6166	Telatinib	332012-40-5	409.83	10mM	c-Kit; PDGFR; VEGFR
T6230	Imatinib	152459-95-5	493.6	10mM	Autophagy; Bcr-Abl; c-Kit; PDGFR; SARS-CoV
T6479	Dovitinib lactate hydrate	915769-50-5	482.51	10mM	c-Kit; FGFR; FLT; PDGFR; VEGFR
T5109	Avapritinib	1703793-34-3	498.56	10mM	c-Kit; PDGFR; PDGFR
T5164	Cabozantinib hydrochloride	1817759-42-4	537.96	10mM	c-Kit; c-Met/HGFR; FLT; ROR; TAM Receptor; VEGFR
T5409	AZD3229	2248003-60-1	479.51	10mM	c-Kit
T7394	Toceranib Phosphate	874819-74-6	494.45	10mM	c-Kit; PDGFR; Tyrosinase; VEGFR
T7861	Flumatinib mesylate	895519-91-2	658.69	10mM	Bcr-Abl; c-Kit; PDGFR
T7945	SU14813	627908-92-3	442.48	10mM	c-Kit; PDGFR; VEGFR
T8482	Ripretinib	1442472-39-0	510.36	10mM	Apoptosis; c-Kit; FLT; PDGFR; VEGFR
T8541	Lenvatinib mesylate	857890-39-2	522.96	10mM	c-Kit; c-RET; FGFR; PDGFR; VEGFR
T15199	Edicotinib	1142363-52-7	461.6	10mM	c-Fms; c-Kit; CSF-1R; FLT
T10157	Regorafénib N-oxyde (M2)	835621-11-9	498.81	10mM	c-Kit; c-RET; Drug Metabolite; PDGFR; Raf; VEGFR
T12145L	N-Desethylsunitinib hydrochloride	1261432-05-6	406.88	10mM	c-Kit; PDGFR; VEGFR
T22349	JNJ-38158471	951151-97-6	364.79	10mM	c-Kit; c-RET; VEGFR
TQ0235	AC710	1351522-04-7	562.7	10mM	c-Kit; FLT; PDGFR
T35570	Chiauranib	1256349-48-0	435.47	10mM	VEGFR;PDGFR;c-Kit;Aurora Kinase;c-Fms;FLT
T41003	KG5	877874-85-6	459.45	10mM	Raf;PDGFR;FLT;c-Kit
T10651	c-Kit-IN-3	2363169-01-9	516.9	10mM	c-Kit
T9689	M4205	2590556-80-0	508.62	10mM	c-Kit
T10803	CHMFL-KIT-033	2351801-41-5	415.42	10mM	c-Kit

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信号通路研究
预实验探索

包装与运输

DMSO溶液置于96孔板中
蓝冰或干冰运输

包装和存储

干粉或者DMSO溶液置于带二维码的储存管中，或排列于96孔板/384孔板；
蓝冰运输

文件下载

化合物库操作手册 (1.89 MB) TargetMol化合物库目录 (13.2 MB) 获取化合物库Excel和SDF列表文件

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty